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Analytical Methods

A peer-reviewed journal highlighting the advancement of analytical technologies for wider application by the international scientific community.



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Paper

Anal. Methods, 2009, 1, 88 - 92, DOI: 10.1039/b9ay00126c

Investigations of optical activity of natural products and chiral pharmaceuticals using liquid crystal technologies

Peter Raynes, Stephen J. Cowling and John W. Goodby

In this article we demonstrate the use of liquid crystal technologies in the determination of enantiomeric excess and in the sensing of molecular chirality, particularly at values near to zero. We use this technique to investigate the optical purities of the commercially available chiral natural product, menthol, and in the investigation of the optical activity of racemic ibuprofen.

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