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Chem. Commun., 2009, 6741 - 6743, DOI: 10.1039/b912850f

Hydroruthenation triggered catalytic conversion of dialdehydes and keto aldehydes to lactones

Sohei Omura, Takahide Fukuyama, Yuji Murakami, Hiromi Okamoto and Ilhyong Ryu

Lactonization of dialdehydes and keto aldehydes was effectively catalyzed by RuHCl(CO)(PPh3)3. A cascade lactonization sequence accompanied by cross-coupling with enones was also attained.

Graphical abstract image for this article (ID: b912850f)