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Chem. Commun., 2009, 5754 - 5756, DOI: 10.1039/b912895f

Palladium-catalysed arylative cyclisation of N-allylacetamides with aryl halides yielding benzyl-substituted oxazolines

Daishi Fujino, Sayuri Hayashi, Hideki Yorimitsu and Koichiro Oshima

Treatment of N-allylacetamide with aryl halide in the presence of sodium t-butoxide and a palladium catalyst leads to arylative cyclisation to provide the corresponding benzyl-substituted oxazoline in high yield.

Graphical abstract image for this article (ID: b912895f)