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Chem. Commun., 2009, 6970 - 6972, DOI: 10.1039/b912907c

Regioselective synthesis of halohydrin esters from epoxides: reaction with acyl halides and rhodium-catalyzed three-component coupling reaction with alkyl halides and carbon monoxide

Koji Nakano, Shunsuke Kodama, Yessi Permana and Kyoko Nozaki

Regioselective synthesis of halohydrin esters was achieved by (1) the reaction of acyl halides with epoxides and (2) the rhodium-catalyzed three-component coupling reaction of alkyl halides, carbon monoxide, and epoxides.

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