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Communication
Chem. Commun., 2009, 6750 - 6752, DOI: 10.1039/b916561d
SERS detection and boron delivery to cancer cells using carborane labelled nanoparticles
David C. Kennedy, Dominique R. Duguay, Li-Lin Tay, Darrin S. Richeson and John P. Pezacki
Water-soluble carborane functionalized nanoparticles also co-functionalized with targeting antibodies have been prepared. We demonstrate tumour cell targeting with anti-EGFR antibodies and delivery of a high concentration of boron using SERS imaging. This suggests these materials have a therapeutic potential in addition to multimodal imaging capabilities.
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