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Dalton Transactions

The international journal for inorganic, organometallic and bioinorganic chemistry



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Dalton Trans., 2007, 3603 - 3605, DOI: 10.1039/b707377a

1-2-Pyrone metal carbonyl complexes as CO-releasing molecules (CO-RMs): A delicate balance between stability and CO liberation

Ian J. S. Fairlamb, Jason M. Lynam, Benjamin E. Moulton, Ian E. Taylor, Anne K. Duhme-Klair, Philip Sawle and Roberto Motterlini

An evaluation of the CO releasing ability of iron(II) and molybdenum(II) complexes has facilitated the discovery of the most rapid CO releaser, namely [Mo(CO)3(5-C5H5)(1-{O}–C{O}–O–CMeCH-COMeCBr)]BF4 (CORM-F10), reported to date. The rate of CO release is related to the overall solution phase stability of the transition metal carbonyl complex. The cytotoxity and vasodilatory properties of CORM-F10 have been determined.

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