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Green Chem., 2009, 11, 1736 - 1742, DOI: 10.1039/b916123f


An efficient aqueous microwave-assisted Suzuki–Miyaura cross-coupling reaction in the thiazole series

Anita Cohen, Maxime D. Crozet, Pascal Rathelot and Patrice Vanelle


A new simple, rapid and high yielding synthesis of various 5-substituted thiazoles by Suzuki–Miyaura cross-coupling reaction is described using microwave irradiation in aqueous medium without organic co-solvent in the presence of tetrabutylammonium bromide.

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