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Green Chem., 2009, 11, 1750 - 1753, DOI: 10.1039/b916583e

Enantioselective aldol reaction of cyclic ketones with aryl aldehydes catalyzed by a cyclohexanediamine derived salt in the presence of water

Jin-Hong Lin, Cheng-Pan Zhang and Ji-Chang Xiao

Water was found to be a suitable reaction medium for the direct asymmetric aldol reaction of various cyclic ketones with aryl aldehydes catalyzed by a primary-tertiary diamine-Brønsted acid.

Graphical abstract image for this article (ID: b916583e)