Lab on a Chip Articles

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Microfluidic & nanofluidic technologies for chemistry, physics, biology, and bioengineering

Advance Articles for Lab on a Chip

First published on the web: 19�November�2009

Design and evaluation of flow distributors for microfabricated pillar array columns
Joris Vangelooven, Wim De Malsche, Jeff Op De Beeck, Hamed Eghbali, Han Gardeniers and Gert Desmet,� Lab Chip, 2010
DOI: 10.1039/b916126k

Chamber and microfluidic probe for microperfusion of organotypic brain slices
Arthur Queval, Nageswara R. Ghattamaneni, C�cile M. Perrault, Raminder Gill, Maryam Mirzaei, R. Anne McKinney and David Juncker,� Lab Chip, 2010
DOI: 10.1039/b916669f

Lithographically patterned silicon nanowire arrays for matrix free LDI-TOF/MS analysis of lipids
Alexander Muck, Thomas Stelzner, Uwe H�bner, Silke Christiansen and Ale Svato,� Lab Chip, 2010
DOI: 10.1039/b913212k

First published on the web: 18�November�2009

Selective trapping and concentration of nanoparticles and viruses in dual-height nanofluidic channels
Mark N. Hamblin, Jie Xuan, Daniel Maynes, H. Dennis Tolley, David M. Belnap, Adam T. Woolley, Milton L. Lee and Aaron R. Hawkins,� Lab Chip, 2010
DOI: 10.1039/b916746c

Optical path-length modulation for three-dimensional particle measurement in mirror-embedded microchannels
Sungyoung Choi, Seung-Hoon Kim and Je-Kyun Park,� Lab Chip, 2010
DOI: 10.1039/b915047a

Generation of water�ionic liquid droplet pairs in soybean oil on microfluidic chip
Xuan Feng, Ying Yi, Xu Yu, Dai-Wen Pang and Zhi-Ling Zhang,� Lab Chip, 2010
DOI: 10.1039/b918167a

Research Highlights
Lab Chip, 2010
DOI: 10.1039/b923816f

First published on the web: 17�November�2009

Spatially resolved shear distribution in microfluidic chip for studying force transduction mechanisms in cells
Jianbin Wang, Jinseok Heo and Susan Z. Hua,� Lab Chip, 2010
DOI: 10.1039/b914874d

A novel far-field nanoscopic velocimetry for nanofluidics
Cuifang Kuang and Guiren Wang,� Lab Chip, 2010
DOI: 10.1039/b917584a

First published on the web: 16�November�2009

Magnetic connectors for microfluidic applications
Javier Atencia, Gregory A. Cooksey, Andreas Jahn, Justin M. Zook, Wyatt N. Vreeland and Laurie E. Locascio,� Lab Chip, 2010
DOI: 10.1039/b913331c

Microfabricated arrays for high-throughput screening of cellular response to cyclic substrate deformation
Christopher Moraes, Jan-Hung Chen, Yu Sun and Craig A. Simmons,� Lab Chip, 2010
DOI: 10.1039/b914460a

Capture of circulating tumor cells from whole blood of prostate cancer patients using geometrically enhanced differential immunocapture (GEDI) and a prostate-specific antibody
Jason P. Gleghorn, Erica D. Pratt, Denise Denning, He Liu, Neil H. Bander, Scott T. Tagawa, David M. Nanus, Paraskevi A. Giannakakou and Brian J. Kirby,� Lab Chip, 2010
DOI: 10.1039/b917959c

Ultralow power trapping and fluorescence detection of single particles on an optofluidic chip
S. K�hn, B. S. Phillips, E. J. Lunt, A. R. Hawkins and H. Schmidt,� Lab Chip, 2010
DOI: 10.1039/b915750f

Magnetically controlled rotation and torque of uniaxial microactuators for lab-on-a-chip applications
Andrea Ranzoni, Xander J. A. Janssen, Mikhail Ovsyanko, Leo J. van IJzendoorn and Menno W. J. Prins,� Lab Chip, 2010
DOI: 10.1039/b909998k

First published on the web: 13�November�2009

High flow rate microfluidic device for blood plasma separation using a range of temperatures
Angeles Iv�n Rodr�guez-Villarreal, Martin Arundell, Manuel Carmona and Josep Samitier,� Lab Chip, 2010
DOI: 10.1039/b904531g

Electrotaxis of Caenorhabditis elegans in a microfluidic environment
Pouya Rezai, Asad Siddiqui, Ponnambalam Ravi Selvaganapathy and Bhagwati P. Gupta,� Lab Chip, 2010
DOI: 10.1039/b917486a

First published on the web: 12�November�2009

A packaged optical slot-waveguide ring resonator sensor array for multiplex label-free assays in labs-on-chips
C. F. Carlborg, K. B. Gylfason, A. Kamierczak, F. Dortou, M. J. Ba�uls Polo, A. Maquieira Catala, G. M. Kresbach, H. Sohlstr�m, T. Moh, L. Vivien, J. Popplewell, G. Ronan, C. A. Barrios, G. Stemme and W. van der Wijngaart,� Lab Chip, 2010
DOI: 10.1039/b914183a

A palmtop PCR system with a disposable polymer chip operated by the thermosiphon effect
Kwang Hyo Chung, Se Ho Park and Yo Han Choi,� Lab Chip, 2010
DOI: 10.1039/b915022f

A vapor-assisted method for adhering polydimethylsiloxane and glass
Aarash Y. N. Sofla and Cristina Martin,� Lab Chip, 2010
DOI: 10.1039/b917295e

First published on the web: 11�November�2009

Ionogel-based light-actuated valves for controlling liquid flow in micro-fluidic manifolds
Fernando Benito-Lopez, Robert Byrne, Ana Maria Rdu, Nihal Engin Vrana, Garrett McGuinness and Dermot Diamond,� Lab Chip, 2010
DOI: 10.1039/b914709h

First published on the web: 10�November�2009

Research Highlights
Lab Chip, 2009
DOI: 10.1039/b922116f

A nano-needle/microtubule composite gliding on a kinesin-coated surface for target molecule transport
Mehmet C. Tarhan, Ryuji Yokokawa, C�line Bottier, Dominique Collard and Hiroyuki Fujita,� Lab Chip, 2010
DOI: 10.1039/b913312g

Precompetitive preclinical ADME/Tox data: set it free on the web to facilitate computational model building and assist drug development
Sean Ekins and Antony J. Williams,� Lab Chip, 2010
DOI: 10.1039/b917760b

Low-power microfluidic electro-hydraulic pump (EHP)
Clarissa Lui, Scott Stelick, Nathaniel Cady and Carl Batt,� Lab Chip, 2010
DOI: 10.1039/b911973f

First published on the web: 29�October�2009

Ultrafast high-pressure AC electro-osmotic pumps for portable biomedical microfluidics
Chien-Chih Huang, Martin Z. Bazant and Todd Thorsen,� Lab Chip, 2009
DOI: 10.1039/b915979g

Microfluidic probe: a new tool for integrating microfluidic environments and electronic wafer-probing
David A. Routenberg and Mark A. Reed,� Lab Chip, 2010
DOI: 10.1039/b913912e

First published on the web: 22�October�2009

Perfused multiwell plate for 3D liver tissue engineering
Karel Domansky, Walker Inman, James Serdy, Ajit Dash, Matthew H. M. Lim and Linda G. Griffith,� Lab Chip, 2010
DOI: 10.1039/b913221j

First published on the web: 19�October�2009

A low power, on demand electrothermal valve for wireless drug delivery applications
Po-Ying Li, Tina K. Givrad, Roya Sheybani, Daniel P. Holschneider, Jean-Michel I. Maarek and Ellis Meng,� Lab Chip, 2009
DOI: 10.1039/b910248e

First published on the web: 16�October�2009

Co-culture of epithelial cells and bacteria for investigating host�pathogen interactions
Jeongyun Kim, Manjunath Hegde and Arul Jayaraman,� Lab Chip, 2009
DOI: 10.1039/b911367c

Field-effect based attomole titrations in nanoconfinement
Rogier B. H. Veenhuis, Egbert J. van der Wouden, Jan W. van Nieuwkasteele, Albert van den Berg and Jan C. T. Eijkel,� Lab Chip, 2009
DOI: 10.1039/b913384d

First published on the web: 15�October�2009

Rapid integrated biosensor for multiplexed immunoassays based on actuated magnetic nanoparticles
D. M. Bruls, T. H. Evers, J. A. H. Kahlman, P. J. W. van Lankvelt, M. Ovsyanko, E. G. M. Pelssers, J. J. H. B. Schleipen, F. K. de Theije, C. A. Verschuren, T. van der Wijk, J. B. A. van Zon, W. U. Dittmer, A. H. J. Immink, J. H. Nieuwenhuis and M. W. J. Prins,� Lab Chip, 2009
DOI: 10.1039/b913960e

Multifunctional plasmonic sensors on low-cost subwavelength metallic nanoholes arrays
Valentin Canpean and Simion Astilean,� Lab Chip, 2009
DOI: 10.1039/b914235e

Rapid multicomponent optical protein patterning
Jonathan M. B�lisle, Dario Kunik and Santiago Costantino,� Lab Chip, 2009
DOI: 10.1039/b911967a

Micro contactor based on isotachophoretic sample transport
Gabriele Goet, Tobias Baier and Steffen Hardt,� Lab Chip, 2009
DOI: 10.1039/b914466h

First published on the web: 13�October�2009

Highly parallel introduction of nucleic acids into mammalian cells grown in microwell arrays
Tilak Jain, Ryan McBride, Steven Head and Enrique Saez,� Lab Chip, 2009
DOI: 10.1039/b913794g

Sequential processing from cell lysis to protein assay on a chip enabling the optimization of an F₁-ATPase single molecule assay condition
Tetsuya Nakayama, Moriaki Namura, Kazuhito V. Tabata, Hiroyuki Noji and Ryuji Yokokawa,� Lab Chip, 2009
DOI: 10.1039/b911148d

First published on the web: 12�October�2009

2D-PCR: a method of mapping DNA in tissue sections
Michael Armani, Jaime Rodriguez-Canales, John Gillespie, Michael Tangrea, Heidi Erickson, Michael R. Emmert-Buck, Benjamin Shapiro and Elisabeth Smela,� Lab Chip, 2009
DOI: 10.1039/b910807f

A blood sampling microsystem for pharmacokinetic applications: Design, fabrication, and initial results
Tao Li, Adam Barnett, Karen L. Rogers and Yogesh B. Gianchandani,� Lab Chip, 2009
DOI: 10.1039/b910508e

Microfluorimeter with disposable polymer chip for detection of coeliac disease toxic gliadin
Teresa Mairal, Ines Frese, Enrique Llaudet, Carmen Bermudo Redondo, Ioanis Katakis, Frithjof von Germar, Klaus Drese and Ciara K. O' Sullivan,� Lab Chip, 2009
DOI: 10.1039/b914635k

Detection of viruses with molecularly imprinted polymers integrated on a microfluidic biochip using contact-less dielectric microsensors
Gerald M. Birnbaumer, Peter A. Lieberzeit, Lukas Richter, Romana Schirhagl, Marcus Milnera, Franz L. Dickert, Andrew Bailey and Peter Ertl,� Lab Chip, 2009
DOI: 10.1039/b914738a

Centrifugo-pneumatic valve for metering of highly wetting liquids on centrifugal microfluidic platforms
Daniel Mark, Tobias Metz, Stefan Haeberle, Sascha Lutz, Jens Ducr�e, Roland Zengerle and Felix von Stetten,� Lab Chip, 2009
DOI: 10.1039/b914415c

An automated, pre-programmed, multiplexed, hydraulic microvalve
Jitae Kim, Dafeng Chen and Haim H. Bau,� Lab Chip, 2009
DOI: 10.1039/b914865e

Room-temperature intermediate layer bonding for microfluidic devices
Jacob Bart, Roald Tiggelaar, Menglong Yang, Stefan Schlautmann, Han Zuilhof and Han Gardeniers,� Lab Chip, 2009
DOI: 10.1039/b914270c

First published on the web: 09�October�2009

Macro- and microscale fluid flow systems for endothelial cell biology
Edmond W. K. Young and Craig A. Simmons,� Lab Chip, 2009
DOI: 10.1039/b913390a

Counting single molecules in sub-nanolitre droplets
T. D. Rane, C. M. Puleo, K. J. Liu, Y. Zhang, A. P. Lee and T. H. Wang,� Lab Chip, 2009
DOI: 10.1039/b917503b