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Lab on a Chip

Microfluidic & nanofluidic technologies for chemistry, physics, biology, and bioengineering



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Technical Note

Lab Chip, 2008, 8, 622 - 624, DOI: 10.1039/b719029h


Shrinky-Dink microfluidics: 3D polystyrene chips

Chi-Shuo Chen, David N. Breslauer, Jesus I. Luna, Anthony Grimes, Wei-chun Chin, Luke P. Lee and Michelle Khine


We present a novel approach for the ultra-rapid direct patterning of complex three-dimensional, stacked polystyrene (PS) microfluidic chips. By leveraging the inherent shrinkage properties of biaxially pre-stressed thermoplastic sheets, microfluidic channels become thinner and deeper upon heating. Design conception to fully functional chips can thus be completed within minutes.

Graphical abstract image for this article  (ID: b719029h)