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Research at the interface between chemistry and the -omic sciences and systems biology.
Advance Articles for Molecular BioSystems
First published on the web: 16 November 2009
Random network behaviour of protein structures
K. V. Brinda, Saraswathi Vishveshwara and Smitha Vishveshwara,
Mol. BioSyst., 2010
DOI: 10.1039/b903019k
Expansion of the mycobacterial 
PUPylome
Jeramie Watrous, Kristin Burns, Wei-Ting Liu, Anand Patel, Vivian Hook, Vineet Bafna, Clifton E. Barry 3rd, Steve Bark and Pieter C. Dorrestein,
Mol. BioSyst., 2010
DOI: 10.1039/b916104j
First published on the web: 12 November 2009
Therapeutic applications of hyaluronan
John Gaffney, Sabine Matou-Nasri, Marta Grau-Olivares and Mark Slevin,
Mol. BioSyst., 2010
DOI: 10.1039/b910552m
Combining nanotechnology with current biomedical knowledge for the vascular imaging and treatment of atherosclerosis
M. Slevin, L. Badimon, M. Grau-Olivares, M. Ramis, J. Sendra, M. Morrison and J. Krupinski,
Mol. BioSyst., 2010
DOI: 10.1039/b916175a
First published on the web: 03 November 2009
Protein intrinsic disorder and oligomericity in cell signaling
Alexander B. Sigalov,
Mol. BioSyst., 2010
DOI: 10.1039/b916030m
First published on the web: 26 October 2009
Limitations of current therapies to prevent thrombosis: a need for novel strategies
Jean-Etienne Fabre and Mark E. Gurney,
Mol. BioSyst., 2010
DOI: 10.1039/b914375k
First published on the web: 19 October 2009
Temperature and salt concentration alter base-sequence selectivity of a duplex DNA-binding protein
Satoru Nagatoishi, Yoshikazu Tanaka, Motonori Kudou and Kouhei Tsumoto,
Mol. BioSyst., 2010
DOI: 10.1039/b914828k
Enhanced HTML article available
Complex genetic regulation of protein glycosylation
Gordan Lauc, Igor Rudan, Harry Campbell and Pauline M. Rudd,
Mol. BioSyst., 2010
DOI: 10.1039/b910377e
Detection of single nucleotide polymorphisms using a DNA Holliday junction nanoswitch—a high-throughput fluorescence lifetime assay
Colin D. McGuinness, Mira K. Y. Nishimura, David Keszenman-Pereyra, Paul Dickinson, Colin J. Campbell, Till T. Bachmann, Peter Ghazal and Jason Crain,
Mol. BioSyst., 2010
DOI: 10.1039/b913455g Enhanced HTML article available
SecB—A chaperone dedicated to protein translocation
Philipp Bechtluft, Nico Nouwen, Sander J. Tans and Arnold J. M. Driessen,
Mol. BioSyst., 2010
DOI: 10.1039/b915435c
Recent advances and novel approaches in deriving neurons from stem cells
Steven J. Greco and Pranela Rameshwar,
Mol. BioSyst., 2010
DOI: 10.1039/b914822c
First published on the web: 16 October 2009
The use of network analyses for elucidating mechanisms in cardiovascular disease
Diego Diez, Åsa M. Wheelock, Susumu Goto, Jesper Z. Haeggström, Gabrielle Paulsson-Berne, Göran K. Hansson, Ulf Hedin, Anders Gabrielsen and Craig E. Wheelock,
Mol. BioSyst., 2010
DOI: 10.1039/b912078e
First published on the web: 14 October 2009
Tripod amphiphiles for membrane protein manipulation
Pil Seok Chae, Philip D. Laible and Samuel H. Gellman,
Mol. BioSyst., 2010
DOI: 10.1039/b915162c
First published on the web: 13 October 2009
A strategy to discover inhibitors of Bacillus subtilis surfactin-type phosphopantetheinyl transferase
Adam Yasgar, Timothy L. Foley, Ajit Jadhav, James Inglese, Michael D. Burkart and Anton Simeonov,
Mol. BioSyst., 2010
DOI: 10.1039/b913291k Enhanced HTML article available
First published on the web: 08 October 2009
A miniaturized screen for inhibitors of Jumonji histone demethylases
Masaaki Sakurai, Nathan R. Rose, Lena Schultz, Amy M. Quinn, Ajit Jadhav, Stanley S. Ng, Udo Oppermann, Christopher J. Schofield and Anton Simeonov,
Mol. BioSyst., 2010
DOI: 10.1039/b912993f Enhanced HTML article available
First published on the web: 06 October 2009
Poly(methyl methacrylate)-graft-oligoamines as low cytotoxic and efficient nonviral gene vectors
Yong-Qiang Wang, Yun-Xia Sun, Xin-Lin Hong, Xian-Zheng Zhang and Gao-Yong Zhang,
Mol. BioSyst., 2010
DOI: 10.1039/b915718b
On-the-fly
optical encoding of combinatorial peptide libraries for profiling of protease specificity
Lionel Marcon, Bronwyn J. Battersby, Andreas Rühmann, Kym Ford, Matthew Daley, Gwendolyn A. Lawrie and Matt Trau,
Mol. BioSyst., 2010
DOI: 10.1039/b909087h Enhanced HTML article available
First published on the web: 30 September 2009
SCOP/PHLPP and its functional role in the brain
Kimiko Shimizu, Scott M. Mackenzie and Daniel R. Storm,
Mol. BioSyst., 2010
DOI: 10.1039/b911410f Enhanced HTML article available
First published on the web: 29 September 2009
Rapid identification of orexin receptor binding ligands using cell-based screening accelerated with magnetic beads
Xin Qi, John Astle and Thomas Kodadek,
Mol. BioSyst., 2010
DOI: 10.1039/b915611a
In vivo proton HR-MAS NMR metabolic profile of the freshwater cladoceran Daphnia magna
Andrei Bunescu, Jeanne Garric, Bernard Vollat, Emmanuelle Canet-Soulas, Danielle Graveron-Demilly and Florence Fauvelle,
Mol. BioSyst., 2010
DOI: 10.1039/b915417e Enhanced HTML article available
Comparison of the interactomic networks of different species in terms of accessibility
Francisco A. Rodrigues and Luciano da Fontoura Costa,
Mol. BioSyst., 2010
DOI: 10.1039/b906966f Enhanced HTML article available
First published on the web: 28 September 2009
Predicting protein–protein interactions in the context of protein evolution
Anna C. F. Lewis, Ramazan Saeed and Charlotte M. Deane,
Mol. BioSyst., 2010
DOI: 10.1039/b916371a
The influence of EDTA and citrate anticoagulant addition to human plasma on information recovery from NMR-based metabolic profiling studies
Richard H. Barton, Daniel Waterman, Frank W. Bonner, Elaine Holmes, Robert Clarke, the PROCARDIS Consortium, Jeremy K. Nicholson and John C. Lindon,
Mol. BioSyst., 2010
DOI: 10.1039/b907021d Enhanced HTML article available
First published on the web: 25 September 2009
Effect of clustered peptide binding on DNA condensation
Jennifer Haley, Paul Kabiru and Yan Geng,
Mol. BioSyst., 2010
DOI: 10.1039/b908873c Enhanced HTML article available
Biomolecule detection with peroxidase-mimicking DNAzymes; expanding detection modality with fluorogenic compounds
Shizuka Nakayama and Herman O. Sintim,
Mol. BioSyst., 2010
DOI: 10.1039/b916228c Enhanced HTML article available
Dynamical effects of epigenetic silencing of 14-3-3
expression
Julio Vera, Julia Schultz, Saleh Ibrahim, Yvonne Raatz, Olaf Wolkenhauer and Manfred Kunz,
Mol. BioSyst., 2010
DOI: 10.1039/b907863k Enhanced HTML article available
First published on the web: 22 September 2009
Molecular recognition of poly(A) targeting by protoberberine alkaloids: in vitro biophysical studies and biological perspectives
Prabal Giri and Gopinatha Suresh Kumar,
Mol. BioSyst., 2010
DOI: 10.1039/b910706a
Amino acid transport in thermophiles: characterization of an arginine-binding protein in Thermotoga maritima
Matthew S. Luchansky, Bryan S. Der, Sabato DAuria, Gabriella Pocsfalvi, Luisa Iozzino, Daniela Marasco and Jonathan D. Dattelbaum,
Mol. BioSyst., 2010
DOI: 10.1039/b908412f Enhanced HTML article available
A residue outside the active site CXXC motif regulates the catalytic efficiency of Glutaredoxin 3
Talia Shekhter, Norman Metanis, Philip E. Dawson and Ehud Keinan,
Mol. BioSyst., 2010
DOI: 10.1039/b912753d Enhanced HTML article available
First published on the web: 21 September 2009
Competitively selected protein ligands pay their increase in specificity by a decrease in affinity
Silke Hoffmann, Susanne Aileen Funke, Katja Wiesehan, Susanne Moedder, Julian Marius Glück, Sophie Feuerstein, Matthias Gerdts, Jessica Mötter and Dieter Willbold,
Mol. BioSyst., 2010
DOI: 10.1039/b910945e Enhanced HTML article available
First published on the web: 18 September 2009
PerR vs OhrR: selective peroxide sensing in Bacillus subtilis
Victor Duarte and Jean-Marc Latour,
Mol. BioSyst., 2010
DOI: 10.1039/b915042k
First published on the web: 14 September 2009
Selective oxidative demethylation of veratric acid to vanillic acid by CYP199A4 from Rhodopseudomonas palustris HaA2
Stephen G. Bell, Adrian B. H. Tan, Eachan O. D. Johnson and Luet-Lok Wong,
Mol. BioSyst., 2009
DOI: 10.1039/b913487e Enhanced HTML article available
First published on the web: 07 September 2009
Cross-species analysis of the glycolytic pathway by comparison of molecular interaction fields
Matthias Stein, Razif R. Gabdoulline and Rebecca C. Wade,
Mol. BioSyst., 2009
DOI: 10.1039/b912398a Enhanced HTML article available
First published on the web: 04 September 2009
Alternate dab-aegPNAs: synthesis, nucleic acid binding studies and biological activity
Giovanni N. Roviello, Domenica Musumeci, Andrea De Cristofaro, Domenica Capasso, Sonia Di Gaetano, Enrico M. Bucci and Carlo Pedone,
Mol. BioSyst., 2009
DOI: 10.1039/b910278g Enhanced HTML article available
Metabolic profiling of the fission yeast S. pombe: quantification of compounds under different temperatures and genetic perturbation
Tomá
Pluskal, Takahiro Nakamura, Alejandro Villar-Briones and Mitsuhiro Yanagida,
Mol. BioSyst., 2009
DOI: 10.1039/b908784b Enhanced HTML article available
Methodological considerations in the development of HPLC-MS methods for the analysis of rodent plasma for metabonomic studies
Lindsay Lai, Filippos Michopoulos, Helen Gika, Georgios Theodoridis, Robert W. Wilkinson, Rajesh Odedra, Julie Wingate, Ron Bonner, Stephen Tate and Ian D. Wilson,
Mol. BioSyst., 2009
DOI: 10.1039/b910482h Enhanced HTML article available
Incorporation of unnatural amino acids for synthetic biology
Natalya Voloshchuk and Jin Kim Montclare,
Mol. BioSyst., 2010
DOI: 10.1039/b909200p
First published on the web: 03 September 2009
Of proteins and DNA—proteomic role in the field of chromatin research
Jean-Philippe Lambert, Kristin Baetz and Daniel Figeys,
Mol. BioSyst., 2009
DOI: 10.1039/b907925b Enhanced HTML article available
First published on the web: 02 September 2009
Genome-scale modeling and in silico analysis of mouse cell metabolic network
Suresh Selvarasu, Iftekhar A. Karimi, Ghi-Hoon Ghim and Dong-Yup Lee,
Mol. BioSyst., 2009
DOI: 10.1039/b912865d Enhanced HTML article available
First published on the web: 01 September 2009
Transcriptional control of the quorum sensing response in yeast
Arthur Wuster and M. Madan Babu,
Mol. BioSyst., 2009
DOI: 10.1039/b913579k Enhanced HTML article available
First published on the web: 28 August 2009
High-confidence mapping of chemical compounds and protein complexes reveals novel aspects of chemical stress response in yeast
Thiago M. Venancio, S. Balaji and L. Aravind,
Mol. BioSyst., 2009
DOI: 10.1039/b911821g Enhanced HTML article available
First published on the web: 27 August 2009
Small-molecule modulators of the Sonic Hedgehog signaling pathway
Benjamin Z. Stanton and Lee F. Peng,
Mol. BioSyst., 2009
DOI: 10.1039/b910196a Enhanced HTML article available
First published on the web: 24 August 2009
Transcriptional control of the proliferation cluster by the tumor suppressor p53
Ran Brosh and Varda Rotter,
Mol. BioSyst., 2009
DOI: 10.1039/b911416e Enhanced HTML article available
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