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Natural Product Reports

High impact, critical reviews in natural products research and related areas




Bioinorganic



Bioinorganic natural products work is now well established as a topic in NPR. Recent examples can be found below.

The chemistry and biochemistry of heme c: functional bases for covalent attachment
Sarah E. J. Bowman and Kara L. Bren, Nat. Prod. Rep., 2008, 25, 1118
DOI: 10.1039/b717196j
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The Janus nature of heme
Thomas L. Poulos, Nat. Prod. Rep., 2007, 24, 504
DOI: 10.1039/b604195g
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Heme and virulence: how bacterial pathogens regulate, transport and utilize heme
Angela Wilks and Kimberly A. Burkhard, Nat. Prod. Rep., 2007, 24, 511
DOI: 10.1039/b604193k
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Structure and catalytic mechanism of heme oxygenase
Masaki Unno, Toshitaka Matsui and Masao Ikeda-Saito, Nat. Prod. Rep., 2007, 24, 553
DOI: 10.1039/b604180a
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Reactivity patterns of cytochrome P450 enzymes: multifunctionality of the active species, and the two states–two oxidants conundrum
Sason Shaik, Hajime Hirao and Devesh Kumar, Nat. Prod. Rep., 2007, 24, 533
DOI: 10.1039/b604192m
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Variations on a (t)heme—novel mechanisms, redox partners and catalytic functions in the cytochrome P450 superfamily
Andrew W. Munro, Hazel M. Girvan and Kirsty J. McLean, Nat. Prod. Rep., 2007, 24, 585
DOI: 10.1039/b604190f
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Structural modelling of metal ion binding to human haemopexin
Marcia R. Mauk, Federico I. Rosell and A. Grant Mauk, Nat. Prod. Rep., 2007, 24, 523
DOI: 10.1039/b604184c
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Spectroscopic characterization of heme iron–nitrosyl species and their role in NO reductase mechanisms in diiron proteins
Pierre Moënne-Loccoz, Nat. Prod. Rep., 2007, 24, 610
DOI: 10.1039/b604194a
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Heme to protein linkages in mammalian peroxidases: impact on spectroscopic, redox and catalytic properties
Martina Zederbauer, Paul G. Furtmüller, Silvia Brogioni, Christa Jakopitsch, Giulietta Smulevich and Christian Obinger, Nat. Prod. Rep., 2007, 24, 571
DOI: 10.1039/b604178g
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Diversity and conservation of interactions for binding heme in b-type heme proteins
Sabine Schneider, Jon Marles-Wright, Katherine H. Sharp and Max Paoli, Nat. Prod. Rep., 2007, 24, 621
DOI: 10.1039/b604186h
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Properties of an unusual heme cofactor in PLP-dependent cystathionine -synthase
Sangita Singh, Peter Madzelan and Ruma Banerjee, Nat. Prod. Rep., 2007, 24, 631
DOI: 10.1039/b604182p
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