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Natural Product Reports

High impact, critical reviews in natural products research and related areas



Pharmacology and drug discovery



Natural product pharmacology and drug discovery are core areas to NPR. Here are some of our recent articles.

Lessons learned from the contamination of heparin
Haiying Liu, Zhenqing Zhang and Robert J. Linhardt, Nat. Prod. Rep., 2009, 26, 313
DOI: 10.1039/b819896a
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Natural products to drugs: natural product-derived compounds in clinical trials
Mark S. Butler, Nat. Prod. Rep., 2008, 25, 475
DOI: 10.1039/b514294f
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Recent advances in the chemistry, biosynthesis and pharmacology of rapamycin analogs
Edmund I. Graziani, Nat. Prod. Rep., 2009, 26, 602
DOI: 10.1039/b804602f
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Isolation, biology and chemistry of the disorazoles: new anti-cancer macrodiolides
Chad D. Hopkins and Peter Wipf, Nat. Prod. Rep., 2009, 26, 585
DOI: 10.1039/b813799b
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Development of Yondelis® (trabectedin, ET-743). A semisynthetic process solves the supply problem
Carmen Cuevas and Andrés Francesch, Nat. Prod. Rep., 2009, 26, 322
DOI: 10.1039/b808331m
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Design of biologically active heparan sulfate and heparin using an enzyme-based approach
Sherket Peterson, Amber Frick and Jian Liu, Nat. Prod. Rep., 2009, 26, 610
DOI: 10.1039/b803795g
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Knipholone and related 4-phenylanthraquinones: structurally, pharmacologically, and biosynthetically remarkable natural products
Gerhard Bringmann, Joan Mutanyatta-Comar, Michael Knauer and Berhanu M. Abegaz, Nat. Prod. Rep., 2008, 25, 696
DOI: 10.1039/b803784c
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