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Natural Product Reports

High impact, critical reviews in natural products research and related areas



Read NPR's Highlight Articles



Highlights: short articles reviewing recent work, bringing into focus topics of both general and specialist interest

Electrodes for integral membrane enzymes
Lars J. C. Jeuken, Nat. Prod. Rep., 2009, 26, 1234
DOI: 10.1039/b903252e
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Synthesis and stereochemical determination of the spirastrellolides
Ian Paterson and Stephen M. Dalby, Nat. Prod. Rep., 2009, 26, 865
DOI: 10.1039/b906991g
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Bioinformatic perspectives on NRPS/PKS megasynthases: Advances and challenges
Holger Jenke-Kodama and Elke Dittmann, Nat. Prod. Rep., 2009, 26, 874
DOI: 10.1039/b810283j
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The isolation, total synthesis and structure elucidation of chlorofusin, a natural product inhibitor of the p53–MDM2 protein–protein interaction
Ryan C. Clark, Sang Yeul Lee, Mark Searcey and Dale L. Boger, Nat. Prod. Rep., 2009, 26, 465
DOI: 10.1039/b821676b
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Lessons learned from the contamination of heparin
Haiying Liu, Zhenqing Zhang and Robert J. Linhardt, Nat. Prod. Rep., 2009, 26, 313
DOI: 10.1039/b819896a
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Heterologous expression systems for polyketide synthases
Isao Fujii, Nat. Prod. Rep., 2009, 26, 155
DOI: 10.1039/b817092b
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Naturally diverse: highlights in versatile synthetic methods enabling target- and diversity-oriented synthesis
Jared T. Shaw, Nat. Prod. Rep., 2009, 26, 11
DOI: 10.1039/b814468k
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2008

Computational enzymology: insight into biological catalysts from modelling
Marc W. van der Kamp and Adrian J. Mulholland, Nat. Prod. Rep., 2008, 25, 1001
DOI: 10.1039/b600517a

Tedanolide and the evolution of polyketide inhibitors of eukaryotic protein synthesis
Richard E. Taylor, Nat. Prod. Rep., 2008, 25, 854
DOI: 10.1039/b805700c

Isoprenoid-like alkylations in polyketide biosynthesis
Christopher T. Calderone, Nat. Prod. Rep., 2008, 25, 845
DOI: 10.1039/b807243d

Syntheses of the tedanolides
Myriam Roy and Markus Kalesse, Nat. Prod. Rep., 2008, 25, 862
DOI: 10.1039/b719607e

Metabolic engineering of microorganisms for isoprenoid production
James Kirby and Jay D. Keasling, Nat. Prod. Rep., 2008, 25, 656
DOI: 10.1039/b802939c

Evolution of polyketides: post-PKS processing in the formation of spiroketals
Jeanette Young and Richard E. Taylor, Nat. Prod. Rep., 2008, 25, 651
DOI: 10.1039/b719088n

Mycolactones: immunosuppressive and cytotoxic polyketides produced by aquatic mycobacteria
Hui Hong, Caroline Demangel, Sacha J. Pidot, Peter F. Leadlay and Tim Stinear, Nat. Prod. Rep., 2008, 25, 447
DOI: 10.1039/b803101k

Mutasynthesis, chemobiosynthesis, and back to semi-synthesis: combining synthetic chemistry and biosynthetic engineering for diversifying natural products
Jonathan Kennedy, Nat. Prod. Rep., 2008, 25, 25
DOI: 10.1039/b707678a

The role of ligand-containing loops at copper sites in proteins
Christopher Dennison, Nat. Prod. Rep., 2008, 25, 15
DOI: 10.1039/b707987g

2007

Myxobacterial natural product assembly lines: fascinating examples of curious biochemistry
Silke Christine Wenzel and Rolf Müller, Nat. Prod. Rep., 2007, 24, 1211
DOI: 10.1039/b706416k

Some recent advances in the synthesis of polycyclic imidazole-containing marine natural products
Steven M. Weinreb, Nat. Prod. Rep., 2007, 24, 931
DOI: 10.1039/b700206h

Bryozoan metabolites: an ecological perspective
Jasmine H. Sharp, Michael K. Winson and Joanne S. Porter, Nat. Prod. Rep., 2007, 24, 659
DOI: 10.1039/b617546e

The Janus nature of heme
Thomas L. Poulos, Nat. Prod. Rep., 2007, 24, 504
DOI: 10.1039/b604195g

Versatile polyketide enzymatic machinery for the biosynthesis of complex mycobacterial lipids
Rajesh S. Gokhale, Priti Saxena, Tarun Chopra and Debasisa Mohanty, Nat. Prod. Rep., 2007, 24, 267
DOI: 10.1039/b616817p

Marine metabolites: metal binding and metal complexes of azole-based cyclic peptides of marine origin
Anna Bertram and Gerald Pattenden, Nat. Prod. Rep., 2007, 24, 18
DOI: 10.1039/b612600f

2006

Bacterial pathways for degradation of nitroaromatics
Zoe C. Symons and Neil C. Bruce, Nat. Prod. Rep., 2006, 23, 845
DOI: 10.1039/b502796a

Biological formation of pyrroles: Nature's logic and enzymatic machinery
Christopher T. Walsh, Sylvie Garneau-Tsodikova and Annaleise R. Howard-Jones, Nat. Prod. Rep., 2006, 23, 517
DOI: 10.1039/b605245m

Natural products: sources and databases
Melanie Füllbeck, Elke Michalsky, Mathias Dunkel and Robert Preissner, Nat. Prod. Rep., 2006, 23, 347
DOI: 10.1039/b513504b

Recent developments in enzymatic chlorination
Cormac D. Murphy, Nat. Prod. Rep., 2006, 23, 147
DOI: 10.1039/b516588c

Cofactor biosynthesis: an organic chemist's treasure trove
Tadhg P. Begley, Nat. Prod. Rep., 2006, 23, 15
DOI: 10.1039/b207131m