RSC Publishing


Publishing

 

Cover image for Natural Product Reports, select for current issue

Natural Product Reports

High impact, critical reviews in natural products research and related areas



Heme themed issue


30 May 2007

The study of heme-containing proteins, with their varied oxidation states and diverse biological functions, is of great interest to chemists, biophysicists and biologists. Modern structural and molecular biology techniques now make it possible to study the mechanism of heme proteins in a level of detail which would have been unimaginable just a few years ago. 

Issue 3 2007 of NPR is a themed issue, guest edited by Emma Raven (University of Leicester, UK) and Paul Ortiz de Montellano (University of California San Francisco, US), which brings together ten articles by leaders in the field covering the breadth of this exciting area. 

on the front cover of issue 3

The front cover is supplied by Andrew Munro and colleagues, University of Manchester, UK.

Editorial: The chemistry and biochemistry of heme proteins
Nat. Prod. Rep., 2007, 24, 499
DOI: 10.1039/b705901a

The Janus nature of heme
Thomas L. Poulos, Nat. Prod. Rep., 2007, 24, 504
DOI: 10.1039/b604195g

Heme and virulence: how bacterial pathogens regulate, transport and utilize heme
Angela Wilks and Kimberly A. Burkhard, Nat. Prod. Rep., 2007, 24, 511
DOI: 10.1039/b604193k

Structure and catalytic mechanism of heme oxygenase
Masaki Unno, Toshitaka Matsui and Masao Ikeda-Saito, Nat. Prod. Rep., 2007, 24, 553
DOI: 10.1039/b604180a

Reactivity patterns of cytochrome P450 enzymes: multifunctionality of the active species, and the two states–two oxidants conundrum
Sason Shaik, Hajime Hirao and Devesh Kumar, Nat. Prod. Rep., 2007, 24, 533
DOI: 10.1039/b604192m

Variations on a (t)heme—novel mechanisms, redox partners and catalytic functions in the cytochrome P450 superfamily
Andrew W. Munro, Hazel M. Girvan and Kirsty J. McLean, Nat. Prod. Rep., 2007, 24, 585
DOI: 10.1039/b604190f

Structural modelling of metal ion binding to human haemopexin
Marcia R. Mauk, Federico I. Rosell and A. Grant Mauk, Nat. Prod. Rep., 2007, 24, 523
DOI: 10.1039/b604184c

Spectroscopic characterization of heme iron–nitrosyl species and their role in NO reductase mechanisms in diiron proteins
Pierre Moënne-Loccoz, Nat. Prod. Rep., 2007, 24, 610
DOI: 10.1039/b604194a

Heme to protein linkages in mammalian peroxidases: impact on spectroscopic, redox and catalytic properties
Martina Zederbauer, Paul G. Furtmüller, Silvia Brogioni, Christa Jakopitsch, Giulietta Smulevich and Christian Obinger, Nat. Prod. Rep., 2007, 24, 571
DOI: 10.1039/b604178g

Diversity and conservation of interactions for binding heme in b-type heme proteins
Sabine Schneider, Jon Marles-Wright, Katherine H. Sharp and Max Paoli, Nat. Prod. Rep., 2007, 24, 621
DOI: 10.1039/b604186h

Properties of an unusual heme cofactor in PLP-dependent cystathionine -synthase
Sangita Singh, Peter Madzelan and Ruma Banerjee, Nat. Prod. Rep., 2007, 24, 631
DOI: 10.1039/b604182p