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Organic & Biomolecular Chemistry

The international home of synthetic, physical and biomolecular organic chemistry.



Top UK work in OBC



This month we feature some of the top recent UK work that has been published in OBC.

For more information on submitting work to OBC please contact the editorial office.

Conformation and stereodynamics of 2,2-disubstituted N,N-diaryl ureas
Jonathan Clayden, Loïc Lemiègre, Mark Pickworth and Lyn Jones, Org. Biomol. Chem., 2008, 6, 2908
DOI: 10.1039/b802673d
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Stereocontrolled synthesis of lepadiformine A
Barry Lygo, Eirene H. M. Kirton and Christopher Lumley, Org. Biomol. Chem., 2008, 6, 3085
DOI: 10.1039/b805951a
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Diversity-oriented synthesis; a spectrum of approaches and results
Richard J. Spandl, Andreas Bender and David R. Spring, Org. Biomol. Chem., 2008, 6, 1149
DOI: 10.1039/b719372f
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Chemical and biomimetic total syntheses of natural and engineered MCoTI cyclotides
Panumart Thongyoo, Núria Roqué-Rosell, Robin J. Leatherbarrow and Edward W. Tate, Org. Biomol. Chem., 2008, 6, 1462
DOI: 10.1039/b801667d
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Reagent switchable stereoselective (1,2) mannoside mannosylation: OH-2 of mannose is a privileged acceptor
Katie J. Doores and Benjamin G. Davis, Org. Biomol. Chem., 2008, 6, 2692
DOI: 10.1039/b803999m
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The small molecule tool (S)-(-)-blebbistatin: novel insights of relevance to myosin inhibitor design
Cristina Lucas-Lopez, John S. Allingham, Tomas Lebl, Christopher P. A. T. Lawson, Ruth Brenk, James R. Sellers, Ivan Rayment and Nicholas J. Westwood, Org. Biomol. Chem., 2008, 6, 2076
DOI: 10.1039/b801223g
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A sequential enantioselective, organocatalytic route to chiral 1,2-oxazines and chiral pyridazines
Sirirat Kumarn, Alexander J. Oelke, David M. Shaw, Deborah A. Longbottom and Steven V. Ley, Org. Biomol. Chem., 2007, 5, 2678
DOI: 10.1039/b708646f
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Bright molecules with sense, logic, numeracy and utility
A. Prasanna de Silva, Thomas P. Vance, Matthew E. S. West and Glenn D. Wright, Org. Biomol. Chem., 2008, 6, 2468
DOI: 10.1039/b802963f
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Mono- and dicationic short PEG and methylene dioxyalkylglycerols for use in synthetic gene delivery systems
Christopher A. Hurley, John B. Wong, Jimmy Ho, Michele Writer, Scott A. Irvine, M. Jayne Lawrence, Stephen L. Hart, Alethea B. Tabor and Helen C. Hailes, Org. Biomol. Chem., 2008, 6, 2554
DOI: 10.1039/b719702k
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A concise and straightforward total synthesis of (±)-salinosporamide A, based on a biosynthesis model
Nicholas P Mulholland, Gerald Pattenden and Iain A. S. Walters, Org. Biomol. Chem., 2008, 6, 2782
DOI: 10.1039/b803818j
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Development of a practical Buchwald–Hartwig amine arylation protocol using a conveniently prepared (NHC)Pd(R-allyl)Cl catalyst
Mark J. Cawley, F. Geoffrey N. Cloke, Richard J. Fitzmaurice, Stuart E. Pearson, James S. Scott and Stephen Caddick, Org. Biomol. Chem., 2008, 6, 2820
DOI: 10.1039/b801479e
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Multi-vicinal fluoroalkanes: a new class of organofluorine compounds
Luke Hunter and David O'Hagan, Org. Biomol. Chem., 2008, 6, 2843
DOI: 10.1039/b809432b
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Further studies on silatropic carbonyl ene cyclisations: -crotyl(diphenyl)silyloxy aldehyde substrates; synthesis of 2-deoxy-2-C-phenylhexoses
Jeremy Robertson, Stuart P. Green, Michael J. Hall, Andrew J. Tyrrell and William P. Unsworth, Org. Biomol. Chem., 2008, 6, 2628
DOI: 10.1039/b804752a
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Auxotrophic-precursor directed biosynthesis of nonribosomal lipopeptides with modified tryptophan residues
Bagher Amir-Heidari, Jenny Thirlway and Jason Micklefield, Org. Biomol. Chem., 2008, 6, 975
DOI: 10.1039/b718766c
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