In this issue's Emerging Area, David Carbery (University of Bath, UK) discusses recent applications of enamides in organic synthesis, substrates whose combination of reactivity and stability makes them very attractive to the synthetic community. 

The work featured on the outside front cover (above), by Ka Wai Choi and Margaret Brimble (University of Auckland, New Zealand), describes a synthetic study to incorporate a triazole unit as a peptide bond surrogate into a spiroacetal derivative. 

The issue's inside front cover (above) is provided by Ben Feringa and colleagues (University of Groningen, The Netherlands). The communication, which is also a hot article, presents a mild and rapid variation on the classical click reaction of azides and alkynes.