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Organic & Biomolecular Chemistry

The international home of synthetic, physical and biomolecular organic chemistry.



Read OBC's Emerging Areas



Emerging Areas are short, personal accounts of a new area of research. They can be speculative in nature, putting a new area in perspective. These are normally published by invitation of the OBC Editorial Board. However, suggestions from authors are welcome and enquiries regarding the submission of Emerging Areas should be directed to the editor.

Enamides: valuable organic substrates
David R. Carbery, Org. Biomol. Chem., 2008, 6, 3455
DOI: 10.1039/b809319a
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Protein modification for single molecule fluorescence microscopy
Mark S. Dillingham and Mark I. Wallace, Org. Biomol. Chem., 2008, 6, 3031
DOI: 10.1039/b808552h
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Multi-vicinal fluoroalkanes: a new class of organofluorine compounds
Luke Hunter and David O'Hagan, Org. Biomol. Chem., 2008, 6, 2843
DOI: 10.1039/b809432b
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Molecular imprinting of proteins emerging as a tool for protein recognition
Toshifumi Takeuchi and Takayuki Hishiya, Org. Biomol. Chem., 2008, 6, 2459
DOI: 10.1039/b715737c
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Synthesis and photophysical properties of 7-deaza-2-deoxyadenosines bearing bipyridine ligands and their Ru(II)-complexes in position 7
Milan Vrábel, Radek Pohl, Ivan Votruba, Mohsen Sajadi, Sergey A. Kovalenko, Nikolaus P. Ernsting and Michal Hocek, Org. Biomol. Chem., 2008, 6, 2852
DOI: 10.1039/b805632c
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Primary amino acids: privileged catalysts in enantioselective organocatalysis
Li-Wen Xu and Yixin Lu, Org. Biomol. Chem., 2008, 6, 2047
DOI: 10.1039/b803116a
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Organocatalysis: asymmetric cascade reactions catalysed by chiral secondary amines
Xinhong Yu and Wei Wang, Org. Biomol. Chem., 2008, 6, 2037
DOI: 10.1039/b800245m
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Chiral ferrocenes as novel rotary modules for molecular machines
Kazushi Kinbara, Takahiro Muraoka and Takuzo Aida, Org. Biomol. Chem., 2008, 6, 1871
DOI: 10.1039/b718982f
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The role of chemical synthesis in structure elucidation of oxasqualenoids
Yoshiki Morimoto, Org. Biomol. Chem., 2008, 6, 1709
DOI: 10.1039/b801126e
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The synthesis of enantiomerically pure [2.2]paracyclophane derivatives
Gareth J. Rowlands, Org. Biomol. Chem., 2008, 6, 1527
DOI: 10.1039/b800698a
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Frustrated Lewis pairs: a concept for new reactivity and catalysis
Douglas W. Stephan, Org. Biomol. Chem., 2008, 6, 1535
DOI: 10.1039/b802575b
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Recent advances in enantioselective [2 + 2 + 2] cycloaddition
Takanori Shibata and Kyoji Tsuchikama, Org. Biomol. Chem., 2008, 6, 1317
DOI: 10.1039/b720031e
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Molecular dipole engineering: new aspects of molecular dipoles in molecular architecture and their functions
Shunsaku Kimura, Org. Biomol. Chem., 2008, 6, 1143
DOI: 10.1039/b717898k
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PET (positron emission tomography) imaging of biomolecules using metal–DOTA complexes: a new collaborative challenge by chemists, biologists, and physicians for future diagnostics and exploration of in vivo dynamics
Katsunori Tanaka and Koichi Fukase, Org. Biomol. Chem., 2008, 6, 815
DOI: 10.1039/b718157b
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Is vanadium a more versatile target in the activity of primordial life forms than hitherto anticipated?
Dieter Rehder, Org. Biomol. Chem., 2008, 6, 957
DOI: 10.1039/b717565p
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Syntheses of manzacidins: a stage for the demonstration of synthetic methodologies
Takuya Hashimoto and Keiji Maruoka, Org. Biomol. Chem., 2008, 6, 829
DOI: 10.1039/b716062c
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A hitchhiker's guide to G-quadruplex ligands
David Monchaud and Marie-Paule Teulade-Fichou, Org. Biomol. Chem., 2008, 6, 627
DOI: 10.1039/b714772b
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Conformationally rigid proteomimetics: a case study in designing antimicrobial aryl oligomers
Gregory J. Gabriel and Gregory N. Tew, Org. Biomol. Chem., 2008, 6, 417
DOI: 10.1039/b714490n
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Dynamic combinatorial chemistry: on the road to fulfilling the promise
Sylvain Ladame, Org. Biomol. Chem., 2008, 6, 219
DOI: 10.1039/b714599c
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Heterogeneous catalysis with nickel-on-graphite (Ni/Cg)
Tom A. Butler, Elizabeth C. Swift and Bruce H. Lipshutz, Org. Biomol. Chem., 2008, 6, 19
DOI: 10.1039/b714600k
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2007

The development of yoctowells as a basis for modeling biological systems
Sheshanath V. Bhosale and Steven J. Langford, Org. Biomol. Chem., 2007, 5, 3733
DOI: 10.1039/b712821e

Catalytic enantioselective stereoablative reactions: an unexploited approach to enantioselective catalysis
Justin T. Mohr, David C. Ebner and Brian M. Stoltz, Org. Biomol. Chem., 2007, 5, 3571
DOI: 10.1039/b711159m

Engineering proteins with tailored nanomechanical properties: a single molecule approach
Hongbin Li, Org. Biomol. Chem., 2007, 5, 3399
DOI: 10.1039/b710321m

Molecularly imprinted polymers (MIPs): sensing, an explosive new opportunity?
Adam McCluskey, Clovia I. Holdsworth and Michael C. Bowyer, Org. Biomol. Chem., 2007, 5, 3233
DOI: 10.1039/b708660a

-Amino acid-containing hybrid peptides—new opportunities in peptidomimetics
Marie-Isabel Aguilar, Anthony W. Purcell, Romila Devi, Rebecca Lew, Jamie Rossjohn, A. Ian Smith and Patrick Perlmutter, Org. Biomol. Chem., 2007, 5, 2884
DOI: 10.1039/b708507a

Palladium catalyzed arylation for the synthesis of polyarenes
Sergio Pascual, Paula de Mendoza and Antonio M. Echavarren, Org. Biomol. Chem., 2007, 5, 2727
DOI: 10.1039/b707940k

Nanoparticles and cells: good companions and doomed partnerships
Dusica Maysinger, Org. Biomol. Chem., 2007, 5, 2335
DOI: 10.1039/b704275b

Synthesis and properties of the chiral oligonaphthalenes
Kazunori Tsubaki, Org. Biomol. Chem., 2007, 5, 2179
DOI: 10.1039/b703558f

Recent advances in the formation of luminescent lanthanide architectures and self-assemblies from structurally defined ligands
Thorfinnur Gunnlaugsson and Floriana Stomeo, Org. Biomol. Chem., 2007, 5, 1999
DOI: 10.1039/b700232g

Pilicides—small molecules targeting bacterial virulence
Veronica Åberg and Fredrik Almqvist, Org. Biomol. Chem., 2007, 5, 1827
DOI: 10.1039/b702397a

Molecular rotors—fluorescent biosensors for viscosity and flow
Mark A. Haidekker and Emmanuel A. Theodorakis, Org. Biomol. Chem., 2007, 5, 1669
DOI: 10.1039/b618415d

The synthesis of chromenes, chromanes, coumarins and related heterocycles via tandem reactions of salicylic aldehydes or salicylic imines with ,-unsaturated compounds
Yong-Ling Shi and Min Shi, Org. Biomol. Chem., 2007, 5, 1499
DOI: 10.1039/b618984a

DNA meets synthetic polymers—highly versatile hybrid materials
Fikri E. Alemdaroglu and Andreas Herrmann, Org. Biomol. Chem., 2007, 5, 1311
DOI: 10.1039/b617941j

Microwave energy: a versatile tool for the biosciences
Jonathan M. Collins and Nicholas E. Leadbeater, Org. Biomol. Chem., 2007, 5, 1141
DOI: 10.1039/b617084f

Chiral dipeptide mimics possessing a fluoroolefin moiety: a relevant tool for conformational and medicinal studies
Samuel Couve-Bonnaire, Dominique Cahard and Xavier Pannecoucke, Org. Biomol. Chem., 2007, 5, 1151
DOI: 10.1039/b701559c

Photochemical control of biological processes
Douglas D. Young and Alexander Deiters, Org. Biomol. Chem., 2007, 5, 999
DOI: 10.1039/b616410m

Carbohydrate post-glycosylational modifications
Hai Yu and Xi Chen, Org. Biomol. Chem., 2007, 5, 865
DOI: 10.1039/b700034k

Micro reactors: a new tool for the synthetic chemist
Paul Watts and Charlotte Wiles, Org. Biomol. Chem., 2007, 5, 727
DOI: 10.1039/b617327f

Advanced organic synthesis using microreactor technology
Batoul Ahmed-Omer, Johan C. Brandt and Thomas Wirth, Org. Biomol. Chem., 2007, 5, 733
DOI: 10.1039/b615072a

Approaches to high throughput physical organic chemistry
Christophe Portal and Mark Bradley, Org. Biomol. Chem., 2007, 5, 587
DOI: 10.1039/b614923e

Molecular springs, muscles, rheostats, and precessing gyroscopes: from review to preview
Michael J. Marsella, Shohreh Rahbarnia and Nathan Wilmot, Org. Biomol. Chem., 2007, 5, 391
DOI: 10.1039/b613891h

Self-assembled multivalent carbohydrate ligands
Yong-beom Lim and Myongsoo Lee, Org. Biomol. Chem., 2007, 5, 401
DOI: 10.1039/b615744k

A systems perspective to digital structures in molecular analysis
Peyman Najmabadi, James J. La Clair and Michael D. Burkart, Org. Biomol. Chem., 2007, 5, 214
DOI: 10.1039/b614507h

Synthesis of protein–polymer conjugates
Karina L. Heredia and Heather D. Maynard, Org. Biomol. Chem., 2007, 5, 45
DOI: 10.1039/b612355d

OBC Emerging Area Archive 2006

Emerging Areas from 2006

OBC Emerging Area Archive 2005

Emerging Areas from 2005

OBC Emerging Area Archive 2004

Emerging Areas from 2004

OBC Emerging Area Archive 2003

Emerging Areas from 2003