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Emerging Area

Org. Biomol. Chem., 2009, 7, 2835 - 2840, DOI: 10.1039/b904405a


Enantioselective metal-catalyzed activation of strained rings

Tobias Seiser and Nicolai Cramer


Activation of otherwise inert bonds has significant potential in the design of efficient and synthetically useful transformations. While general catalytic carbon–carbon single bond activations are still in their infancy, this emerging area examines recent developments in the activation of strained rings, focusing on enantioselective reactions.

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