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Communication
Org. Biomol. Chem., 2009, 7, 4173 - 4176, DOI: 10.1039/b913400j
Highly enantioselective synthesis of angelmarin
Hang Jiang and Yasumasa Hamada
Angelmarin ( 1), a novel anti-cancer agent, was efficiently synthesized through a highly enantioselective epoxidation and a copper cyanide-mediated esterification of the hindered alcohol as the key steps in 53% overall yield.
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