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Lab on a Chip

Microfluidic and nanotechnologies for chemistry, biology, and bioengineering



Review articles


Review Articles 2008

MEMS and the microbe
Colin J. Ingham and Johan E. T. van Hylckama Vlieg, Lab Chip, 2008, 8, 1604
DOI: 10.1039/b804790a


Microdroplets: A sea of applications?
Ansgar Huebner, Sanjiv Sharma, Monpichar Srisa-Art, Florian Hollfelder, Joshua B. Edel and Andrew J. deMello, Lab Chip, 2008, 8, 1244
DOI: 10.1039/b806405a


Cell research with physically modified microfluidic channels: A review
Sun Min Kim, Sung Hoon Lee and Kahp Yang Suh, Lab Chip, 2008, 8, 1015
DOI: 10.1039/b800835c


Managing evaporation for more robust microscale assays
Part 2. Characterization of convection and diffusion for cell biology

Erwin Berthier, Jay Warrick, Hongmeiy Yu and David J. Beebe, Lab Chip, 2008, 8, 860
DOI: 10.1039/b717423c


Managing evaporation for more robust microscale assays
Part 1. Volume loss in high throughput assays

Erwin Berthier, Jay Warrick, Hongmeiy Yu and David J. Beebe, Lab Chip, 2008, 8, 852
DOI: 10.1039/b717422e


Droplet microfluidics
Shia-Yen Teh, Robert Lin, Lung-Hsin Hung and Abraham P. Lee, Lab Chip, 2008, 8, 198
DOI: 10.1039/b715524g


Biomolecular gradients in cell culture systems
Thomas M. Keenan and Albert Folch, Lab Chip, 2008, 8, 34
DOI: 10.1039/b711887b


Molecular sieving using nanofilters: Past, present and future
Jongyoon Han, Jianping Fu and Reto B. Schoch, Lab Chip, 2008, 8, 23
DOI: 10.1039/b714128a


Review Articles 2007

Continuous flow separations in microfluidic devices
Nicole Pamme, Lab Chip, 2007, 7, 1644
DOI: 10.1039/b712784g


Recent developments of bio-molecular motors as on-chip devices using single molecule techniques
D. Spetzler, J. York, C. Dobbin, J. Martin, R. Ishmukhametov, L. Day, J. Yu, H. Kang, K. Porter, T. Hornung and W. D. Frasch, Lab Chip, 2007, 7, 1633
DOI: 10.1039/b711066a


A decade of microfluidic analysis coupled with electrospray mass spectrometry: An overview
Sander Koster and Elisabeth Verpoorte, Lab Chip, 2007, 7, 1394
DOI: 10.1039/b709706a


Total nucleic acid analysis integrated on microfluidic devices
Lin Chen, Andreas Manz and Philip J. R. Day, Lab Chip, 2007, 7, 1413
DOI: 10.1039/b708362a


Micro- and nanomechanical sensors for environmental, chemical, and biological detection
Philip S. Waggoner and Harold G. Craighead, Lab Chip, 2007, 7, 1238
DOI: 10.1039/b707401h


Microfluidic platforms for lab-on-a-chip applications
Stefan Haeberle and Roland Zengerle, Lab Chip, 2007, 7, 1094
DOI: 10.1039/b706364b


Optical filtering technologies for integrated fluorescence sensors
Marc Dandin, Pamela Abshire and Elisabeth Smela, Lab Chip, 2007, 7, 955
DOI: 10.1039/b704008c


Comparative study and improvement of current cell micro-patterning techniques
Jenny Fink, Manuel Théry, Ammar Azioune, Raphael Dupont, François Chatelain, Michel Bornens and Matthieu Piel, Lab Chip, 2007, 7, 672
DOI: 10.1039/b618545b


A practical guide to microfluidic perfusion culture of adherent mammalian cells
Lily Kim, Yi-Chin Toh, Joel Voldman and Hanry Yu, Lab Chip, 2007, 7, 681
DOI: 10.1039/b704602b


Analysis of single mammalian cells on-chip
Christopher E. Sims and Nancy L. Allbritton, Lab Chip, 2007, 7, 423
DOI: 10.1039/b615235j


Lab-on-a-chip devices for global health: Past studies and future opportunities
Curtis D. Chin, Vincent Linder and Samuel K. Sia, Lab Chip, 2007, 7, 41
DOI: 10.1039/b611455e


Microtechnology: Meet neurobiology
Thomas M. Pearce and Justin C. Williams, Lab Chip, 2007, 7, 30
DOI: 10.1039/b612856b


Review Articles 2006

Microfluidic devices for culturing primary mammalian neurons at low densities
Larry J. Millet, Matthew E. Stewart, Jonathan V. Sweedler, Ralph G. Nuzzo and Martha U. Gillette, Lab Chip, 2007, 7, 987
DOI: 10.1039/b705266a


Proteome-on-a-chip: Mirage, or on the horizon?
Sergio L. S. Freire and Aaron R. Wheeler, Lab Chip, 2006, 6, 1415
DOI: 10.1039/b609871a


Ultrasonic enhancement of bead-based bioaffinity assays
M. Wiklund and H. M. Hertz, Lab Chip, 2006, 6, 1279
DOI: 10.1039/b609184a


Membranes and microfluidics: a review
J. de Jong, R. G. H. Lammertink and M. Wessling, Lab Chip, 2006, 6, 1125
DOI: 10.1039/b603275c


Miniaturised isotachophoresis analysis
Lin Chen, Jeff E. Prest, Peter R. Fielden, Nicholas J. Goddard, Andreas Manz and Philip J. R. Day, Lab Chip, 2006, 6, 474
DOI: 10.1039/b515551g


Miniaturized continuous flow reaction vessels: influence on chemical reactions
Monica Brivio, Willem Verboom and David N. Reinhoudt, Lab Chip, 2006, 6, 329
DOI: 10.1039/b510856j


Magnetism and microfluidics
Nicole Pamme, Lab Chip, 2006, 6, 24
DOI: 10.1039/b513005k


Nanotechnology for membranes, filters and sieves
A series of mini-reviews covering new trends in fundamental and applied research, and potential applications of miniaturised technologies

Lab Chip, 2006, 6, 19
DOI: 10.1039/b516903h


Review Articles 2005

The problem of self-calibration of fluorescence signal in microscale sensor systems
Alexander P. Demchenko, Lab Chip, 2005, 5, 1210
DOI: 10.1039/b507447a


Water in micro- and nanofluidics systems described using the water potential
Jan C. T. Eijkel and Albert van den Berg, Lab Chip, 2005, 5, 1202
DOI: 10.1039/b509819j


Technologies for nanofluidic systems: top-down vs. bottom-up—a review
D. Mijatovic, J. C. T. Eijkel and A. van den Berg, Lab Chip, 2005, 5, 492
DOI: 10.1039/b416951d


Solid supports for micro analytical systems
Dominic S. Peterson, Lab Chip, 2005, 5, 132
DOI: 10.1039/b405311g


Review Articles 2004

Miniaturised nucleic acid analysis
P.-A. Auroux, Y. Koc, A. deMello, A. Manz and P. J. R. Day, Lab Chip, 2004, 4, 534
DOI: 10.1039/b408850f


Macro-to-micro interfaces for microfluidic devices
Carl K. Fredrickson and Z. Hugh Fan, Lab Chip, 2004, 4, 526
DOI: 10.1039/b410720a


Theory and numerical simulation of droplet dynamics in complex flows—a review
Vittorio Cristini and Yung-Chieh Tan, Lab Chip, 2004, 4, 257
DOI: 10.1039/b403226h


Proliferation of microfluidics in literature and intellectual property
Lab Chip, 2004, 4, 16N
DOI: 10.1039/b400810n


Focus
Microscale reactors: nanoscale products

John de Mello and Andrew de Mello, Lab Chip, 2004, 4, 11N
DOI: 10.1039/b403638g


Microfabrication and microfluidics for tissue engineering: state of the art and future opportunities
Helene Andersson and Albert van den Berg, Lab Chip, 2004, 4, 98
DOI: 10.1039/b314469k


Microenvironment design considerations for cellular scale studies
Glenn M. Walker, Henry C. Zeringue and David J. Beebe, Lab Chip, 2004, 4, 91
DOI: 10.1039/b311214d


Review Articles 2003

Focus
Beads and chips: new recipes for analysis

Elisabeth Verpoorte, Lab Chip, 2003, 3, 60N
DOI: 10.1039/b313217j


Focus
Chip vision—optics for microchips

Lab Chip, 2003, 3, 42N
DOI: 10.1039/b307927a


Focus
Seeing single molecules

Lab Chip, 2003, 3, 29N
DOI: 10.1039/b304585b


Focus. Dealing with real samples: sample pre-treatment in microfluidic systems
Andrew J. de Mello and Nigel Beard, Lab Chip, 2003, 3, 11N
DOI: 10.1039/b301019h


Review Articles 2002

FOCUS
Life, the universe and microfluidics

Lab Chip, 2002, 2, 58N
DOI: 10.1039/b210360p


FOCUS
On-chip chromatography: the last twenty years

Andrew de Mello, Lab Chip, 2002, 2, 48N
DOI: 10.1039/b207266c


Focus: Plastic fantastic?
 

Andrew de Mello, Lab Chip, 2002, 2, 31N
DOI: 10.1039/b203828p


Viewpoint: Improving access to microtechnology—the Europractice Project
 

J. Malcolm Wilkinson, Lab Chip, 2002, 2, 37N
DOI: 10.1039/b202417a


FOCUS
But what is it good for? Applications of microreactor technology for the fine chemical industry

Andrew de Mello and Robert Wootton, Lab Chip, 2002, 2, 7N
DOI: 10.1039/b200736n


Review Articles 2001

Focus
DNA amplification: does small really mean efficient?

Andrew J. de Mello, Lab Chip, 2001, 1, 24N
DOI: 10.1039/b109740g


Trends in miniaturized total analysis systems for point-of-care testing in clinical chemistry
Anna J. Tüds, Geert A. J. Besselink and Richard B. M. Schasfoort, Lab Chip, 2001, 1, 83
DOI: 10.1039/b106958f


Recent developments in detection methods for microfabricated analytical devices
Maria A. Schwarz and Peter C. Hauser, Lab Chip, 2001, 1, 1
DOI: 10.1039/b103795c