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Molecular BioSystems

Research at the interface between chemistry and the -omic sciences and systems biology.



Contents list for Molecular BioSystems, issue 9, 2009

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Front cover
Mol. BioSyst., 2009, 5, 881
DOI: 10.1039/b915303a

front cover image for Molecular BioSystems, Issue 9, 2009


Inside front cover
Mol. BioSyst., 2009, 5, 882
DOI: 10.1039/b916247j

Contents and Highlights in Chemical Biology
Mol. BioSyst., 2009, 5, 883
DOI: 10.1039/b915308j

Editorial

Emerging Investigators 2009
Mol. BioSyst., 2009, 5, 895
DOI: 10.1039/b912394f

Profile

Contributors to the Emerging Investigators issue
Mol. BioSyst., 2009, 5, 896
DOI: 10.1039/b913862p

Review

Molecular pathways in tumor progression: from discovery to functional understanding
Muhammad Akhtar Ali and Tobias Sjöblom,  Mol. BioSyst., 2009, 5, 902
DOI: 10.1039/b903502h
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Communications

Metabolic profiling of Helicobacter pylori glycosylation
Maria B. Koenigs, Elizabeth A. Richardson and Danielle H. Dube,  Mol. BioSyst., 2009, 5, 909
DOI: 10.1039/b902178g
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Prenyltransferase substrate binding pocket flexibility and its application in isoprenoid profiling
Youli Xiao, Miranda Machacek, Kent Lee, Tomohisha Kuzuyama and Pinghua Liu,  Mol. BioSyst., 2009, 5, 913
DOI: 10.1039/b902370d
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A fluorogenic dye activated by S-nitrosothiols
Jia Pan, Jonathan A. Downing, Jeanne L. McHale and Ming Xian,  Mol. BioSyst., 2009, 5, 918
DOI: 10.1039/b822283e
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CTAB-induced morphological transition of DNA micro-assembly from filled spheres to hollow capsules
Kazunori Matsuura, Kouzo Masumoto, Yuuko Igami, Kwonil Kim and Nobuo Kimizuka,  Mol. BioSyst., 2009, 5, 921
DOI: 10.1039/b903382c
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Assessment of helical interfaces in protein–protein interactions
Andrea L. Jochim and Paramjit S. Arora,  Mol. BioSyst., 2009, 5, 924
DOI: 10.1039/b903202a
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Identification of 3-hydroxy-2-(3-hydroxyphenyl)-4H-1-benzopyran-4-ones as isoform-selective PKC- inhibitors and potential therapeutics for psychostimulant abuse
Langtian Yuan, Jin-Soo Seo, Nam Sook Kang, Shahar Keinan, Sarah E. Steele, Gregory A. Michelotti, William C. Wetsel, David N. Beratan, Young-Dae Gong, Tong H. Lee and Jiyong Hong,  Mol. BioSyst., 2009, 5, 927
DOI: 10.1039/b903036k
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Improving orthogonal tRNA-synthetase recognition for efficient unnatural amino acid incorporation and application in mammalian cells
Jeffrey K. Takimoto, Katrina L. Adams, Zheng Xiang and Lei Wang,  Mol. BioSyst., 2009, 5, 931
DOI: 10.1039/b904228h
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Papers

Probing phosphorylation by non-mammalian isoprenoid biosynthetic enzymes using 1H–31P–31P correlation NMR spectroscopy
Ananya Majumdar, Meha H. Shah, J. Kipchirchir Bitok, Maria E. Hassis-LeBeau and Caren L. Freel Meyers,  Mol. BioSyst., 2009, 5, 935
DOI: 10.1039/b903513c
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Design, synthesis and biological evaluation of sugar-derived esters, -ketoesters and -ketoamides as inhibitors for Mycobacterium tuberculosis antigen 85C
Aditya K. Sanki, Julie Boucau, Francis E. Umesiri, Donald R. Ronning and Steven J. Sucheck,  Mol. BioSyst., 2009, 5, 945
DOI: 10.1039/b902284h
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The interaction of hyperthermophilic TATA-box binding protein with single-stranded DNA is entropically favorable and exhibits a large negative heat capacity change at high salt concentration
Satoru Nagatoishi, Yoshikazu Tanaka, Motonori Kudou and Kouhei Tsumoto,  Mol. BioSyst., 2009, 5, 957
DOI: 10.1039/b904200h
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Modular synthesis of biologically active phosphatidic acid probes using click chemistry
Matthew D. Smith, Christopher G. Sudhahar, Denghuang Gong, Robert V. Stahelin and Michael D. Best,  Mol. BioSyst., 2009, 5, 962
DOI: 10.1039/b901420a
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Construction of biosensor systems for determining the pathophysiological potential of carrageenan variants
Angela Riedel, Caroline End, Helle Christiansen, Marcus Renner, Christian Bender, Steffen Schmidt, Bernhard Korn, Holger Sueltmann and Jan Mollenhauer,  Mol. BioSyst., 2009, 5, 973
DOI: 10.1039/b901882b
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Peptidic small molecule activators of the stress sensor DegS
Patrick Hauske, Nicolette Mamant, Sonja Hasenbein, Sabrina Nickel, Christian Ottmann, Tim Clausen, Michael Ehrmann and Markus Kaiser,  Mol. BioSyst., 2009, 5, 980
DOI: 10.1039/b902089f
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RNA aptamers selected against amyloid -peptide (A) inhibit the aggregation of A
Tsuyoshi Takahashi, Kosuke Tada and Hisakazu Mihara,  Mol. BioSyst., 2009, 5, 986
DOI: 10.1039/b903391b
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Assessing biological variation and protein processing in primary human leukocytes by automated multiplex stable isotope labeling coupled to 2 dimensional peptide separation
Reinout Raijmakers, Albert J. R. Heck and Shabaz Mohammed,  Mol. BioSyst., 2009, 5, 992
DOI: 10.1039/b901873e
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Computational model and microfluidic platform for the investigation of paracrine and autocrine signaling in mouse embryonic stem cells
David Ellison, Alex Munden and Andre Levchenko,  Mol. BioSyst., 2009, 5, 1004
DOI: 10.1039/b905602e
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Profiling patterns of glutathione reductase inhibition by the natural product illudin S and its acylfulvene analogues
Xiaodan Liu and Shana J. Sturla,  Mol. BioSyst., 2009, 5, 1013
DOI: 10.1039/b904720d
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Probing nanosecond motions of plasminogen activator inhibitor-1 by time-resolved fluorescence anisotropy
Chin Wing Ko, Zhenquan Wei, Richard J. Marsh, Daven A. Armoogum, Nick Nicolaou, Angus J. Bain, Aiwu Zhou and Liming Ying,  Mol. BioSyst., 2009, 5, 1025
DOI: 10.1039/b901691k
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Enhancing the utility of unnatural amino acid synthetases by manipulating broad substrate specificity
Audrey L. Stokes, Shigeki J. Miyake-Stoner, Jennifer C. Peeler, Duy P. Nguyen, Robert P. Hammer and Ryan A. Mehl,  Mol. BioSyst., 2009, 5, 1032
DOI: 10.1039/b904032c
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A quantitative high-throughput screen for modulators of IL-6 signaling: a model for interrogating biological networks using chemical libraries
Ronald L. Johnson, Ruili Huang, Ajit Jadhav, Noel Southall, Jennifer Wichterman, Ryan MacArthur, Menghang Xia, Kun Bi, John Printen, Christopher P. Austin and James Inglese,  Mol. BioSyst., 2009, 5, 1039
DOI: 10.1039/b902021g
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The topology of drug–target interaction networks: implicit dependence on drug properties and target families
Jordi Mestres, Elisabet Gregori-Puigjané, Sergi Valverde and Ricard V. Solé,  Mol. BioSyst., 2009, 5, 1051
DOI: 10.1039/b905821b
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The effect of increasing hydrophobicity on the self-assembly of amphipathic -sheet peptides
Charles J. Bowerman, Derek M. Ryan, David A. Nissan and Bradley L. Nilsson,  Mol. BioSyst., 2009, 5, 1058
DOI: 10.1039/b904439f
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Screening of a branched peptide library with HIV-1 TAR RNA
David I. Bryson, Wenyu Zhang, W. Keith Ray and Webster L. Santos,  Mol. BioSyst., 2009, 5, 1070
DOI: 10.1039/b904304g
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Back matter
Mol. BioSyst., 2009, 5, 1074
DOI: 10.1039/b915309h

Back cover
Mol. BioSyst., 2009, 5, 1075
DOI: 10.1039/b915310c