Ligand exchange

If we add ammonia solution to a solution containing hexaaquacopper(II) ions, [Cu(H2O)6]2+, four of the six water ligands are successively replaced by ammonia molecules to form the tetraamminediaquacopper(II) ion,  [Cu(NH3)4(H2O)2]2+. The process involved is a dynamic equilibrium with ammonia and water molecules moving into and out of the complex ion.

These changes are described in the following equilibrium equation: 

 [Cu(H2O)6]2+(aq) + 4NH3(aq)  [Cu(NH3)4(H2O)2]2+(aq) + 4H2O(l)

                         (light blue solution)                          (dark blue solution)

This type of reaction is called a ligand exchange reaction because some of the water ligands are replaced by ammonia ligands. The change is easy to observe because the solution containing the complex containing ammonia molecules is a much deeper blue than that with the complex containing only water molecule ligands.

If you added water to the solution containing [Cu(NH3)4(H2O)2]2+ ions, what would you expect to see?

The dark blue solution would become lighter as the equilibrium position moves towards the [Cu(H2O)6]2+  ions.

These changes can be seen in the following video clip.

[INSERT LEE_CI_02_vid]

In Magic beakers, Declan Fleming describes a colourful series of changes, several of which involve ligand exchange reactions, while Colin Bakler uses ligand exchange reactions to demonstrate A spectacular reversible reaction.

 
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