Approved training courses
This classroom-based course covers all the considerations and strategic steps for method development, troubleshooting and maintenance. The course material includes interactive problem-solving questions to allow you to implement the strategies learned.
On day 1 we guide you in how to plan and organise the method development process, with a number of recommended strategies, looking at the individual components of the HPLC & LC-MS system, including sampling techniques and identifying the parameters for optimisation, then detailing further. You will then implement the knowledge gained by working through practical method development case studies. Following this, we detail the steps of method validation and the benefits of accreditation.
The day ends by taking a brief look at advanced techniques that can be used for complex samples including detector selectivity and specificity, UHPLC vs. HPLC (brief introduction to method transfer), chromatographic peak deconvolution using tandem mass spectrometry, multi-dimensional LC (LCxLC), on-line SPE and chemometrics.
Day 2 looks at clean-up procedures for difficult samples along with the parts of the HPLC & MS system which require maintenance and how to identify when maintenance is required.
The course details the strategies and processes for HPLC & LC-MS troubleshooting and for each component of the system we identify the problem areas. Delegates can then put this knowledge to the test through practical exercise on troubleshooting chromatograms.
At the end of the course you will have in-depth knowledge of how to approach method development and validation. You will also have learned which areas of the instrument require maintenance and the logical steps in troubleshooting.
Please note, this is a classroom-based course only and does not include any hands-on experience in the laboratory.
The HPLC & LC-MS Clinic course is for those who have reasonable liquid chromatography experience or have attended the Practical Essentials of HPLC & LC-MS or the Complete Hands-on HPLC & LC-MS courses.
Additional infoCourse includes: lunch and refreshments; hard copy of the training manual in colour; certificate of attendance; ability to ask questions and discuss own problems.
Various
Class/lab
2 days
£750.00 GBP (plus VAT)
Find an approved training course
Use the options below to search through the growing list of chemical sciences training courses that have been approved by the Royal Society of Chemistry.
Courses are approved for CPD purposes only; approval does not imply they will fulfill any regulatory requirements.
