Jessie Stow started her career in drug discovery using apprenticeships as a platform to develop her chemical sciences expertise. She undertook her Level 5 apprenticeship in the Analytical Chemistry Department at Takeda Pharmaceuticals, UK, which helped her gain an insight into the drug discovery process and learn key laboratory techniques. In just a year there, she became technically skilled in the use and maintenance of liquid chromatography-mass spectrometry (LC-MS) instruments, which are fundamental tools for quantitative analysis of molecules.
Jessie expanded her knowledge of the pharmaceutical industry by building an understanding of fragment-based drug discovery at Astex Pharmaceuticals. Here, in the Drug Metabolism and Pharmacokinetics (DMPK) team, she applied her LC-MS knowledge to analyse samples following experiments to determine how drugs are absorbed, distributed, metabolised and excreted from the body. These properties, when combined, define the pharmacokinetic (PK) properties of a drug and can be used to predict how a drug will behave in a human. Jessie studied mechanisms of enzymatic drug metabolism to support this work, and this knowledge contributed towards her Honours Degree Apprenticeship in Applied Chemistry with the University of Kent. She then went on to do a Master’s Degree Apprenticeship in Drug Discovery and Development. Alongside this, she began to investigate how chemical technologies can be used to mimic enzymatic mechanisms of drug metabolism. Since then, she has expanded this research to drive the use of biocatalysis as an effective alternative to traditional synthetic methodologies.
Leave congratulations on this page
Please use this space to congratulate the winner, but note that the Royal Society of Chemistry will not respond to any comments or questions left on this page.
If you have a question or would like to get in touch with us, please contact us via this page.
Your comment will appear on this page after it is approved by moderators.
Fields marked with a '*' are mandatory.