Professor Michael Ingleson MRSC
Winner: 2024 Dalton mid-career prize: Sir Geoffrey Wilkinson Prize
University of Edinburgh
For new approaches to C–H borylation using zinc catalysts and bis-borane electrophiles.
Celebrate Professor Michael Ingleson
The Ingleson Group focuses mainly on making molecules called organoboranes using chemical reactions that are generally termed borylations which form boron-carbon bonds. By adding boron to molecules instead of a carbon atom, the group has achieved useful changes in multiple properties.
When these 'borylated' molecules have boron in the 'right place', along with other elements like nitrogen or oxygen, their new properties can be harnessed to create compounds with diverse applications. For example, organoboranes are already used as safe, 'green' reagents in the production of agrochemicals and pharmaceuticals. They have also been extensively explored as emissive materials in organic light-emitting diodes (OLEDs, so they may end up in your phone or TV in the near future) and as active molecules in drugs (including those being used to tackle antibiotic resistance). Therefore, there is an increasing need to make new organoboranes in a sustainable way.
To avoid using rare or toxic metals, the Ingleson Group develops new borylation reactions that use reactive compounds based only on Earth-abundant elements.
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