Additions and corrections

Artificial lantipeptides from in vitro translations

Florian P. Seebeck, Alonso Ricardo and Jack W. Szostak

Chem. Commun., 2011, 6141-6143 (DOI: 10.1039/c0cc05663d) Amendment published 21st July 2011

The structures of peptides B and C in Figure 3 are incorrect and the incorrect sequence was also given in the figure caption. Glu14 was missing from both peptide structures. The correct Figure 3 and caption are presented below.

Note that the calculated and measure mass stated in the figure caption corresponds to the correct peptide. The authors apologise for any confusion caused by this discrepancy.

Fig. 3 The N-terminal domain of nisin consists of two macrocycles which are tailored by lanthionine forming enzymes (structure A). An enzyme-free process is able to produce a similar structure by installing six posttranslational modifications resulting in a peptide with the structure B or, less likely C (B/C, sequence: formylM_NDhbDhVDhbLCDhPGCRLEH6, m/z calcd. 2257.0, found. 2256). Please note that natural lantipeptides (exemplified by structure A) contain Z-Dhb while the chemically modified peptides contain E-Dhb as indicated by the different orientation of the side chain methyl group.

The Royal Society of Chemistry apologises for this error and any consequent inconvenience to authors and readers.

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