File Name : scheme s1.docx

Caption : scheme 1 illustration of the synthesis process of mcs@uio-66-nh<sub>2</sub>/lac complex enzyme and construction of the mcs@uio-66-nh<sub>2</sub>/lac/abts/chit/gce tetracycline biosensor.

File Name : scheme s2.docx

Caption : scheme s2 schematic illustration of the synthesis process of mcs.

File Name : scheme s3.docx

Caption : scheme s3 schematic illustration of the synthesis process of the mcs/uio-66-nh<sub>2</sub> composite.

File Name : fig. s1.docx

Caption : fig. s1 (a) ft-ir spectra of the as-prepared materials: (a) uio-66, (b) uio-66-nh<sub>2</sub> and (c) mcs@uio-66-nh<sub>2</sub>. (b) partial enlarged details of (a).

File Name : fig. s2.docx

Caption : fig. s2 (a) sem image of mcs, (b) particle size distribution histogram obtained from sem image (a), (c) sem image of mcs@uio-66-nh<sub>2</sub>, (d) particle size distribution histogram obtained from sem image (c).

File Name : fig. s3.docx

Caption : fig. s3 effect of the initial laccase solution concentration on the laccase loading on mcs@uio-66-nh<sub>2</sub> composite

File Name : fig. s4.docx

Caption : fig. s4 zeta-potential of mcs@uio-66-nh<sub>2</sub> at the immobilization ph of 6.0.

File Name : fig. s5.docx

Caption : fig. s5 stability of as-prepared biosensors: (a) mcs/uio-66-nh<sub>2</sub>/lac/abts/chit/gce, (b) lac/abts/chit/gce.

File Name : fig. s6.docx

Caption : fig. s6 (a) cvs of mcs@ uio-66-nh<sub>2</sub>/lac/abts/chit/gce biosensor measured at scan rates range 25-200 mv s<sup>-1</sup>. (b) plots of the peak current vs. scan rate

File Name : fig. s7.docx

Caption : fig. s7 effect of the concentration of the mcs@uio-66-nh<sub>2</sub>/lac complex enzyme on the response current of the mcs@uio-66-nh<sub>2</sub>/lac/abts/chit/gce biosensor. 

File Name : fig. s8.docx

Caption : fig. s8 effect of the concentration of abts on the response current of the mcs@uio-66-nh<sub>2</sub>/lac/abts/chit/gce biosensor. 

File Name : fig. s9.docx

Caption : fig. s9 effect of the ph of hac-naac suffer solution on the response current of the mcs@uio-66-nh<sub>2</sub>/lac/abts/chit/gce biosensor.