File Name : s1.tif

Caption : figure s1. the hplc chromatograms of standard substance and gtwe. (1: galli acid; 2: epigallocatechin; 3: catechin; 4: caffeine; 5: epigallocatechin gallate; 6: epicatechin; 7: gallocatechin gallate; 8: epicatechin gallate; 9: ellagic acid)

File Name : s-2.tif

Caption : figure s2. (a) the phylum-level composition and abundance distributions of each group. (b) a heat map of genera at the phylum level. (c) the genus-level composition and abundance distributions of each group. (d) a heat map of genera at the genus level. (e) relative abundance in each group. (f) firmicutes/bacteroidetes ratio. (g) relative genus-level abundance. *p < 0.05, **p < 0.01, ***p < 0.001，****p < 0.0001 compared to the etoh group. data represent mean ± s.d. (n= 3).

File Name : s-3.tif

Caption : figure s3. (a)sequence number percent. (b) the number of taxas. (c) the number of otus. (d) based on the kegg database, the relative abundance of microbiota functions. (e) and (f) relative abundance of microbiota functions based on the third level of the kegg database. *p < 0.05, **p < 0.01, ***p < 0.001，****p < 0.0001 compared to the etoh group. data represent mean ± s.d. (n= 3).