Additions and corrections

History, biology and chemistry of Mycobacterium ulcerans infections (Buruli ulcer disease)

Anne-Caroline Chany, Cédric Tresse, Virginie Casarotto and Nicolas Blanchard

Nat. Prod. Rep., 2013, 30, 1527–1567 (DOI: 10.1039/C3NP70068B ). Amendment published 13th November 2013.

The compound numbering is incorrect in Figure 13. Please find below the corrected figure.




On page 38, 7 compound numbers are incorrect. Lines 32 to 41 should read as follows:

'On the other hand, a significant cytotoxicity was conserved for the analogues of the third class with a LC₅₀ of 15 nM for 113, similar to the one of the natural toxin, indicating that a polar hydroxy group at the C20 position is very well tolerated. Slightly higher LC₅₀ values were measured for 114a (45 nM) and 114b (50 nM). For two selected derivatives (115 and 116), the inhibition of the proliferation of L929 fibroblasts was investigated and it was found that only 116 displayed signifcant inhibition after 72 h. Finally, 116 also induced a transient effect on the actin cytoskeleton as well as a classical rounding up of the fibroblasts.'

The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers.

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