Additions and corrections


Facilitation of displacements at the 6-position of purines by the use of 1,4-diazabicyclo[2.2.2]octane as leaving group

Nicola K. Lembicz, Sharon Grant, William Clegg, Roger J. Griffin, Sarah L. Heath and Bernard T. Golding

J. Chem. Soc., Perkin Trans. 1, 1997, 185


The authors wish to cite two additional references which are relevant to this paper.

The ability of 1,4-diazabicyclo[2.2.2]octane (DABCO) to catalyse reactions of 2-amino-9-benzyl-6-chloro-9H-purine with alkoxides has been demonstrated (J. A. Linn, E. W. McLean and J. L. Kelley, J. Chem. Soc., Chem. Commun., 1994, 913). These authors also characterised 1-(2-amino-9-benzyl-9H-purin-6-yl)-4-aza-1-azoniabicyclo[2.2.2]octane from reaction of DABCO with 2-amino-9-benzyl-6-chloro-9H-purine in dimethylformamide. DABCO has been shown to catalyse reactions of 6-chloropurines with cyanide (M. Hocek and A. Holy, Collect. Czech. Chem. Commun., 1995, 60, 1386).

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