Synopsis
Multiple vital cellular processes are regulated by specific interactions between proteins and examples of pathways mediated by protein-protein interactions (PPIs) include gene expression, proliferation, intracellular communication and apoptosis. Numerous diseases occur because pathways involving particular PPIs malfunction. The challenge is to understand the process by which one protein recognises another and binds to modulate its function. The rewards for a better understanding of particular PPIs include the potential to develop new molecular therapeutics and to develop probes to investigate systems biology. To date, only a few PPIs have been the subject of a drug discovery initiative.Owing to the many opportunities presented by modulation of PPIs, this field has gained increasing scientific interest over the past decade and has seen many innovations from both academic and industrial research groups. This meeting aims to address recent advances in the characterisation and identification of new PPI inhibitors. Topics will include in silico assessment of PPI druggability, assay screening technologies for PPIs, structural biology approaches and fragment based drug design.
Attendees
This event is aimed at all scientists (students, post-docs, academics, industrialists) engaged in research projects on protein-protein interactions or additionally for those scientists interested in finding our more about research on PPIs. The range of topics covered in the meeting will hold appeal to chemists and biologists alike as in addition to covering fundamental elements of PPI research the meeting will be of interest to the drug discovery community eager to understand how the challenges of tackling protein-protein interactions to identify new drugs is being approached and executed across the pharmaceutical industry.Call for posters
Anyone wishing to present a poster is encouraged to submit a one-page abstract toclarice.williams@soci.org with 'PPI 2016 - poster abstract' in the subject line. Selected poster presenters will also be given the opportunity to give a flash presentation. Please use the template provided in the downloads section.Exhibition and sponsorship
Posters and refreshments will be situated in the exhibition area, ensuring excellent access to delegates throughout the meeting. Exhibition places are limited; to book your stand or enquire about sponsorship opportunities, please contact clarice.williams@soci.org for further information and costs.
Registration
Early-bird discounts will be available for this event. To register your interest in attending, please emailconferences@soci.org with the subject line 'PPI 2016 – Register my interest'.
