The need in healthcare to detect biomolecular species such as proteins, oligonucleotides (DNA and RNA) and cells for diagnostics is driving the current development of physical techniques. These techniques are generally based on optical, electrochemical and mass spectrometric transduction. Exploitation in array formats is enabling the development of high throughput detection to inform
systems biology and pathway medicine, giving new insights into biomolecular pathways and identifying new target analytes.
This is a highly topical and exciting area which opens up the real prospect of theranostics (the use of diagnostics in informing patient specific therapy). However, development and optimisation of detection requires an understanding and control of the fundamental physical processes occurring both in sensing and signal transduction and assessing the comparative merits of alternative detection strategies. For high throughput detection, bioinformatics (the processing and interpretation of vast amounts of data) also presents a real challenge.
This meeting offers a unique opportunity to discuss the relative merits of these physical methods, and the fundamental issues which currently hinder or preclude their development and utilisation. These discussions will be informed by the requirements for detection (the “clinical pull”) and for systems development (the “technological pull”).
Themes
Faraday Discussion 149, organised by the Faraday Division, aims to bring together scientists from many disciplines, including
biologists, physicists and chemists, involving academics and industrialists from the healthcare and biosensing communities.
Scientific Committee
Andrew Mount (Chair)
University of Edinburgh, UK
Till Bachmann
University of Edinburgh, UK
Phil Bartlett
University of Southampton, UK
Rob Beynon
University of Liverpool, UK
Mark Bradley
University of Edinburgh, UK
Paul French
Imperial College, London, UK
David Mendels
Cognoscens, France
Invited Speakers
Roger Tsien (Introductory)
University of California, San Diego, USA
Pankaj Vadgama (Closing)
Queen Mary University of London, UK
Nancy Allbritton
University of North Carolina, USA
Tony Cass
Imperial College London, UK
Graham Cooks
Purdue University, USA
Kev Dhaliwal
MRC Centre for Inflammation Research,
Edinburgh, UK
Walter Kolch
University College Dublin, Ireland
systems biology and pathway medicine, giving new insights into biomolecular pathways and identifying new target analytes.
This is a highly topical and exciting area which opens up the real prospect of theranostics (the use of diagnostics in informing patient specific therapy). However, development and optimisation of detection requires an understanding and control of the fundamental physical processes occurring both in sensing and signal transduction and assessing the comparative merits of alternative detection strategies. For high throughput detection, bioinformatics (the processing and interpretation of vast amounts of data) also presents a real challenge.
This meeting offers a unique opportunity to discuss the relative merits of these physical methods, and the fundamental issues which currently hinder or preclude their development and utilisation. These discussions will be informed by the requirements for detection (the “clinical pull”) and for systems development (the “technological pull”).
Themes
- Systems/Devices to Inform Therapy (SDIT)
- Physical Techniques for Diagnostics (PTD)
- High-Throughput Measurement and Analysis (HTMA)
- Towards Real-time Clinical Measurement (TRCM)
Faraday Discussion 149, organised by the Faraday Division, aims to bring together scientists from many disciplines, including
biologists, physicists and chemists, involving academics and industrialists from the healthcare and biosensing communities.
Scientific Committee
Andrew Mount (Chair)
University of Edinburgh, UK
Till Bachmann
University of Edinburgh, UK
Phil Bartlett
University of Southampton, UK
Rob Beynon
University of Liverpool, UK
Mark Bradley
University of Edinburgh, UK
Paul French
Imperial College, London, UK
David Mendels
Cognoscens, France
Invited Speakers
Roger Tsien (Introductory)
University of California, San Diego, USA
Pankaj Vadgama (Closing)
Queen Mary University of London, UK
Nancy Allbritton
University of North Carolina, USA
Tony Cass
Imperial College London, UK
Graham Cooks
Purdue University, USA
Kev Dhaliwal
MRC Centre for Inflammation Research,
Edinburgh, UK
Walter Kolch
University College Dublin, Ireland
