RSC Desktop Seminars in Organic Chemistry with the Brazilian Chemical Society 2020 are an initiative from the Royal Society of Chemistry and the Brazilian Chemical Society to bring cutting-edge research directly to you!
Covid-19 has exposed us to a new reality where the virtual world is much more important than before. In order to keep our students engaged at the frontiers of Organic Chemistry, we have organized a weekly webinar series that is a joint collaboration between the Royal Society of Chemistry (RSC) and the Organic Chemistry Division of the Brazilian Chemical Society (SBQ). It is an alternative way to share work and interact with potential collaborators.
The sections will alternate between Brazilian and international speakers, in some cases with the opportunity for a selected Brazilian early career researcher to engage with the audience by presenting their recent independent career developments.
11:35 Early Career presentation with Q&A
11:55 Main Speaker with Q&A
12:55 Closing remarks
13:00 Close
TMS-Aryl Trifluoromethanesulfonates in Benzyne Chemistry: Limitations and New Challenges
Benzyne and its derivatives, called arynes, are highly reactive intermediates, with recognized importance in organic chemistry, successfully employed in syntheses of natural products and preparations of functional materials. In this context, TMS-aryl trifluoromethanesulfonates have emerged as an important alternative for the formation of benzyne and arynes under mild reaction conditions, enlarging the scope of benzyne chemistry applications in preparative organic chemistry. However, some limitations related to their synthetic routes still need to be overcome, for example, the requirement for n-butyllithium, that is, a strong and nucleophilic base, as well as the use of trifluoromethanesulfonic anhydride or bis(trifluoromethanesulfonyl)aniline as triflating reagents. Thus, through this lecture we intend to present our advances and some challenges involving the preparation of novel classes of aryne precursors.
Fernanda Gadini Finelli
Investigations on drug discovery and process development through photoredox and organocatalysis
Catalysis is a key technology in the pursuit of sustentability for a wide range of processes. In the last decades, photoredox and organocatalysis have been inserted in this scenario promoting more direct synthetic routes with optimization of time and energy. In this talk, I will present some recent advances from my research group in this area towards the synthesis of bioactive compounds and the development of processes employing immobilized organocatalysts in continuous flow systems.
Covid-19 has exposed us to a new reality where the virtual world is much more important than before. In order to keep our students engaged at the frontiers of Organic Chemistry, we have organized a weekly webinar series that is a joint collaboration between the Royal Society of Chemistry (RSC) and the Organic Chemistry Division of the Brazilian Chemical Society (SBQ). It is an alternative way to share work and interact with potential collaborators.
The sections will alternate between Brazilian and international speakers, in some cases with the opportunity for a selected Brazilian early career researcher to engage with the audience by presenting their recent independent career developments.
Programme
11:30 Introductions and welcome11:35 Early Career presentation with Q&A
11:55 Main Speaker with Q&A
12:55 Closing remarks
13:00 Close
Speakers
Cristiano RaminelliTMS-Aryl Trifluoromethanesulfonates in Benzyne Chemistry: Limitations and New Challenges
Benzyne and its derivatives, called arynes, are highly reactive intermediates, with recognized importance in organic chemistry, successfully employed in syntheses of natural products and preparations of functional materials. In this context, TMS-aryl trifluoromethanesulfonates have emerged as an important alternative for the formation of benzyne and arynes under mild reaction conditions, enlarging the scope of benzyne chemistry applications in preparative organic chemistry. However, some limitations related to their synthetic routes still need to be overcome, for example, the requirement for n-butyllithium, that is, a strong and nucleophilic base, as well as the use of trifluoromethanesulfonic anhydride or bis(trifluoromethanesulfonyl)aniline as triflating reagents. Thus, through this lecture we intend to present our advances and some challenges involving the preparation of novel classes of aryne precursors.
Fernanda Gadini Finelli
Investigations on drug discovery and process development through photoredox and organocatalysis
Catalysis is a key technology in the pursuit of sustentability for a wide range of processes. In the last decades, photoredox and organocatalysis have been inserted in this scenario promoting more direct synthetic routes with optimization of time and energy. In this talk, I will present some recent advances from my research group in this area towards the synthesis of bioactive compounds and the development of processes employing immobilized organocatalysts in continuous flow systems.
