RSC Medicinal Chemistry Desktop Seminar Series

Amanda E. Hargrove is an Associate Professor of Chemistry at Duke University. Prof. Hargrove earned her Ph.D. in Organic Chemistry from the University of Texas at Austin followed by an NIH postdoctoral fellowship at Caltech. Prof. Hargrove’s laboratory at Duke focuses on developing small molecule probes to investigate the structure and function of RNA molecules relevant to human disease. The lab works to understand the fundamental drivers of selective small molecule:RNA recognition and to use this knowledge to functionally modulate viral and oncogenic RNA structures. You can find out more about their research by visiting the laboratory webpage.
 
Congruent with the interdisciplinary nature of this program, Prof. Hargrove holds a secondary appointment in the Biochemistry Department and membership in the Duke Cancer Institute, the Pharmaceutical Sciences Training Program, and the Center for Biological and Tissue Engineering. Recent honours include the Sloan Research Fellowship, ChemComm Emerging Investigator Lectureship, RSC Medicinal Chemistry Emerging Investigator Lectureship, NSF CAREER Award, Cottrell Scholar Award, and Prostate Cancer Young Investigator Award.

Jean-Louis Reymond is a Professor of Chemistry at the University of Bern, Switzerland. He studied Chemistry and Biochemistry at the ETH Zürich and obtained his Ph.D. at the University of Lausanne on natural products synthesis (1989). After a Post-Doc and Assistant Professorship at the Scripps Research Institute, he joined the University of Bern (1997). His research focuses on the enumeration and visualization of chemical space for small molecule drug discovery, the synthesis of new molecules from GDB (http://gdb.unibe.ch), and the design and synthesis of peptide dendrimers and polycyclic peptides as antimicrobials and for nucleic acids delivery. He is the author of >300 scientific publications and reviews.